Basal cell carcinoma of the groin and buttocks: a clinical and histological analysis of a rare presentation of a common tumor

Abstract

Background Basal cell carcinoma (BCC) is a common tumor but rarely presents on nonexposed skin. We sought to identify and characterize the traits of the malignancy over a 10-year period.Methods A retrospective chart review of all BCCs between 2007 and 2017 was performed. Clinical characteristics and histological features were evaluated.Results Of all BCCs biopsied in a 10-year period, 53 tumors in 50 patients were diagnosed in the groin or buttocks. This accounts for 0.094% of all BCCs during this time period. None of the cases had genetic diseases prone to skin cancer development or were immunosuppressed. The most common location was the buttocks, and the most frequently diagnosed histological subtype was nodular (49%).Conclusion To our knowledge, this is the largest report of BCC of the groin and buttocks.In this rare presentation of a common tumor, the histological characteristics of it are not more aggressive than other sites on the body.

Nodular Basal Cell Carcinoma in an Unusual Groin Location: A Rare Presentation

“…Histologically, the most frequent subtypes described on the groin region were nodular (as in our reported case), superficial and infiltrative [ 3 , 4 ].…”

“…BCC occurs in the groin region in a minority of patients. In one study made on patients diagnosed to have BCC, between the years 2007 and 2017, the occurrence in the groin was estimated at 0.094% [ 3 ]. Another larger study reported an incidence of 0.27% [ 4 ].…”

“…When located in the groin, BCC presents no tendency to aggressive behavior, compared to BCCs occurring elsewhere in the body [ 3 ].…”

Basal cell carcinoma at an eccentric location: A rare case report

“…where they did a chart review of all BCCs between 2007 and 2017, only 0.094% of all BCCs occurred in the groin or buttocks. [ 1 ] The varied manifestation gives rise to various clinical subtypes and is classified into superficial, nodular, pigmented, ulcerating, cystic, sclerosing,[ 6 ] and polypoid[ 7 8 ] patterns. Histological variants are nodular, micronodular, fibroepithelial, adenoid, morpheaform, infiltrative,[ 7 ] and polypoid[ 8 ] types.…”

“…Basal cell carcinoma (BCC) is the most common form of skin cancer,[ 1 ] which presents with local invasion, has low metastasizing potential[ 2 ] and a cure rate of 100% after surgical excision. It has been attributed to be the most prevalent cancer type among white-skinned populations and is uncommon in Asians and Black African races.…”