Baseline Demographics and Clinical Characteristics in the All Nippon AF in the Elderly (ANAFIE) Registry

Age-Related Differences in the Clinical Characteristics and Treatment of Elderly Patients With Atrial Fibrillation in Japan ― Insight From the ANAFIE (All Nippon AF In Elderly) Registry ―

“…[29][30][31] The ANAFIE registry was designed to obtain real-world information on patients with NVAF aged ≥75 years, including current status, current anticoagulant therapy, and prognosis. 32, 33 The aim of this analysis of ANAFIE registry data was to compare age-related differences in clinical characteristics and treatment between age groups in a large cohort of elderly Japanese patients with AF.…”

“…32 Registry UMIN000024006) is a multicenter, prospective, observational (non-interventional) registry of elderly NVAF patients (aged ≥75 years) from across Japan; full details of the registry have been reported previously. 32, 33 Patient enrollment in the registry started in October 2016 (target, 30,000 patients), and follow-up data were collected at month 12 and month 24. 32 Ethics approval was obtained from all relevant institutional review boards, and all patients provided written informed consent and were free to withdraw from the registry at any time.…”

“…A total of 33,278 patients were registered, 33 32,726 of whom were included in this analysis. Prior to enrollment, 163 patients were excluded, primarily due to duplicate registrations (n=85) or withdrawal of consent (n=76; Figure 1).…”

Rhythm versus rate control strategies regarding anticoagulant use in elderly non-valvular atrial fibrillation patients: Subanalysis of the ANAFIE (All Nippon AF In the Elderly) Registry

“…The study design and baseline clinical characteristics of the ANAFIE registry have been reported elsewhere [23,24]. Briefly, the ANAFIE registry was initiated in October 2016 and was a multicenter, prospective, observational study incorporating a minimum 2-year follow-up for each patient [23].…”

Baseline Characteristics of Elderly Japanese Patients Aged ≥75 Years With Non-Valvular Atrial Fibrillation and a History of Stroke ― ANAFIE Registry ―

“…The aim of ANAFIE was to clarify the clinical and therapeutic characteristics of these patients (including anticoagulation use), such as thromboembolism, major bleeding, and death occurring during observation, and the risk factors associated with each event. 13,14 The rate of IS in AF patients taking anticoagulants decreased from 46.7 per 1,000 patient-years in 1992 to 19.5 in 2002. 15 However, the annual incidence of life-threatening or severe bleeding for Japanese AF patients was 2.06% during anticoagulation, increasing to 3.56% when an antiplatelet agent was added, 16 which is higher than in the population without anticoagulation.…”