Baseline Health-Related Quality of Life in Postmenopausal Women with Coronary Heart Disease: The Estrogen Replacement and Atherosclerosis (ERA) Trial

Abstract

These data suggest that both clinical status variables (particularly chest pain) and the psychosocial context (represented by dimensions of relationship quality) influenced HRQL in this cohort. Thus, interventions that combine medical treatments with psychosocially based interventions may be most effective for women at risk for impaired HRQL.

Narrative review of health‐related quality of life and its predictors among patients with coronary heart disease

“…One study used SF‐36 to measure HRQoL and found low HRQoL scores, highlighting the failure to return to premorbid status . It reported lower Mental and Physical Component Summary scores among CHD patients compared with the healthy population .…”

“…One study used SF‐36 to measure HRQoL and found low HRQoL scores, highlighting the failure to return to premorbid status . It reported lower Mental and Physical Component Summary scores among CHD patients compared with the healthy population . The reliability of these findings was further supported when Wang and colleagues used both a disease‐specific instrument (MIDAS) and a generic questionnaire (SF‐36), obtaining poor HRQoL scores from both instruments.…”

Gender Differences in Coronary Heart Disease and Health-Related Quality of Life: Findings from 10 States from the 2004 Behavioral Risk Factor Surveillance System

“…[32][33][34][35] In a Swedish study conducted from 1989 to 1991, 413 patients with an acute MI were compared with 88 population controls. 32 Patients with acute MI perceived their health status as worse 1 month and 1 year after their event.…”

“…34 On the other hand, among 301 US women in the Estrogen Replacement and Atherosclerosis (ERA) trial, a previous MI did not significantly predict scores of either the Physical Component Summary or Mental Component Summary of the SF-36. 33 …”

Predictors of quality of life among women with coronary heart disease

“…Previous studies have reported negative correlates of QOL in individuals with heart disease including younger age, being unmarried, being unemployed, and having comorbid medical conditions [4][5][6][7][8][9][10]. However, prior studies have had limited sample sizes and primarily consisted of white, middle-aged male patients, despite the fact that coronary heart disease (CHD) is the leading cause of death and premature disability among women in the nation and that CHD disproportionately afflicts ethnic minorities [11].…”