Baseline heavy metals and metalloid values in blood of loggerhead turtles (Caretta caretta) from Baja California Sur, Mexico

Ley‐Quiñónez, César P.; Zavala‐Norzagaray, Alan A.; Espinosa-Carreón, T. Leticia; Peckham, Howard H.; Márquez-Herrera, C.; Campos-Villegas, Lorena Elizabeth; Aguirre, A. Alonso

doi:10.1016/j.marpolbul.2011.06.022

Cited by 69 publications

(43 citation statements)

References 28 publications

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“…For low-dose chronic exposure of heavy metals, blood sample is generally considered a better indicator as it can reflect the recent comprehensive information of various elements in human body (Ley-Quinonez et al 2011). Cadmium in urine and blood is a widely used biomarker for assessing cadmium exposure or body burden of cadmium in general population (Jarup et al 1998).…”

Section: Discussionmentioning

confidence: 99%

Cadmium exposure and the risk of breast cancer in Chaoshan population of southeast China

Lin

Huang

Zhang

et al. 2015

Environ Sci Pollut Res

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Recently, there is increasing evidence indicating a link between cadmium exposure and human breast cancer. This study was aimed to explore the relationship between blood cadmium burden and the risk of breast cancer in Chaoshan women with no occupational exposure. Blood cadmium levels (BCLs) were determined in whole blood of 186 breast cancer cases and 139 controls. Basic clinical data and information of age, occupation, blood types, family cancer history, and disease history, as well as other demographic characteristics were collected from medical records. BCLs were detected by graphite-furnace atomizer absorption spectrophotometer (GFAAS). BCLs and proportions of BCLs over 3 μg/L between cases and controls were compared. The relationships between BCLs and breast cancer were explored by comparing BCL differences between/among different characteristics of investigated factors. In addition, BCLs within cases were also compared in relation to the disease clinical stages, tumor-node-metastasis (TNM) stages, and estrogen receptor (ER), progesterone receptor (PR), and Cerb-B2 expressions. The breast cancer patients had a higher median concentration of blood cadmium (2.28, interquartile range 1.57-3.15 μg/L) than the controls (1.77, 1.34-2.57 μg/L; P = 0.001). The proportion of BCLs over 3 μg/L was 2.35 times higher in the breast cancer cases than that of the controls after adjusting for age. Cadmium tends to accumulate in the human body with age and body mass index (BMI) but not associates with type of job, family history, disease history, and other investigated characters. With the increase of clinical stages and T and M stages, the BCLs in the breast cancer cases also increased. BCLs were positively associated with Cerb-B2 expression (r = 0.152, P = 0.038) but not significantly associated with ER and PR expressions. The data obtained show that cadmium concentration is significantly higher in blood of breast cancer patients in comparison to healthy controls. Cadmium seems to be a risk factor of breast cancer, and high cadmium exposure was observed in advanced stages of this disease, which indicates that it may promote the development of breast cancer.

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Section: Discussionmentioning

confidence: 99%

Cadmium exposure and the risk of breast cancer in Chaoshan population of southeast China

Lin

Huang

Zhang

et al. 2015

Environ Sci Pollut Res

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“…Many reports have demonstrated elevated levels of heavy metals in aquatic turtles (Ley-Quinonez et al 2011;Yu et al 2011). Furthermore, in response to lead toxicity in children in Mexico, Pellalo-Martinez et al (2011) observed Sliders (Trachemys scripta) in the area to contain twice the lead concentration than in the children.…”

Section: Introductionmentioning

confidence: 99%

Select metal and metalloid surveillance of free-ranging Eastern box turtles from Illinois and Tennessee (Terrapene carolina carolina)

et al. 2015

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The Eastern box turtle (Terrapene carolina carolina) is a primarily terrestrial chelonian distributed across the eastern US. It has been proposed as a biomonitor due to its longevity, small home range, and reliance on the environment to meet its metabolic needs. Plasma samples from 273 free-ranging box turtles from populations in Tennessee and Illinois in 2011 and 2012 were evaluated for presence of heavy metals and to characterize hematologic variables. Lead (Pb), arsenic (As), zinc (Zn), chromium (Cr), selenium (Se), and copper (Cu) were detected, while cadmium (Cd) and silver (Ag) were not. There were no differences in any metal detected among age class or sex. However, Cr and Pb were higher in turtles from Tennessee, while As, Zn, Se, and Cu were higher in turtles from Illinois. Seasonal differences in metal concentrations were observed for Cr, Zn, and As. Health of turtles was assessed using hematologic variables. Packed cell volume was positively correlated with Cu, Se, and Pb in Tennessee. Total solids, a measure of plasma proteins, in Tennessee turtles were positively correlated with Cu and Zn. White blood cell count, a measure of inflammation, in Tennessee turtles was negatively correlated with Cu and As, and positively correlated with Pb. Metals are a threat to human health and the health of an ecosystem, and the Eastern Box Turtle can serve as a monitor of these contaminants. Differences established in this study can serve as baseline for future studies of these or related populations.

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“…blood sampling is an excellent, relatively noninvasive method to establish reliable baseline values of element levels in healthy sea turtles [7,11,14]. Van de Merwe et al [21] used blood samples to estimate the liver, kidney and muscle accumulation of elements in green sea turtles at found strong correlations between blood and tissue concentrations of As, cd, co, Hg and Se.…”

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confidence: 99%

Relationships between Carapace Sizes and Plasma Major and Trace Element Status in Captive Hawksbill Sea Turtles (<i>Eretmochelys imbricata</i>)

Suzuki

Noda

Yanagisawa

et al. 2012

The Journal of Veterinary Medical Science

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AbSTRAcT. The aim of this study was to evaluate the relationships between carapace parameters as indicators of age and plasma elements in 25 captive hawksbill sea turtles. Particle-induced X-ray emission allowed detection of 23 trace and major elements. There were significant but weak correlations between the virtual carapace surface area and plasma bromide (r= −0.552, P<0.01), phosphorus (r=0.547, P<0.01), lead (r=−0.434, P<0.05) and strontium (r=0.599, P<0.01), while there were no significant correlations with other elements. These results suggest that major and trace plasma elements in captive sea turtles show almost no variation with carapace parameters, suggesting that the increase in plasma elements seen in wild sea turtles might be the result of marine pollution. KEY WORDS: carapace size, hawksbill sea turtle, major elements, marine ecosystem, trace elements.

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Baseline heavy metals and metalloid values in blood of loggerhead turtles (Caretta caretta) from Baja California Sur, Mexico

Cited by 69 publications

References 28 publications

Cadmium exposure and the risk of breast cancer in Chaoshan population of southeast China

Cadmium exposure and the risk of breast cancer in Chaoshan population of southeast China

Select metal and metalloid surveillance of free-ranging Eastern box turtles from Illinois and Tennessee (Terrapene carolina carolina)

Relationships between Carapace Sizes and Plasma Major and Trace Element Status in Captive Hawksbill Sea Turtles (<i>Eretmochelys imbricata</i>)

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