Baseline musculoskeletal pain and impaired sleep related to school pressure influence the development of musculoskeletal pain in N = 107 adolescents in a 5-year longitudinal study

Salathé, Cornelia Rolli; Kälin, Wolfgang; Zilse, S.

doi:10.1007/s00586-019-06211-x

Cited by 3 publications

(2 citation statements)

References 27 publications

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“…We have recently shown in four studies in children, adolescents and adults, that a history of iron deficiency is associated, probably causally, with multiple pain conditions [66] (see Supplementary Information). Other shared risk factors for multiple pain conditions include some bidirectional factors such as impaired sleep [67][68][69], restless legs syndrome [56,70], early childhood adversity [71,72], although bias [73] is acknowledged, and anxiety and depression [74][75][76][77]. Consistent with the anxiety and depression studies cited, both categories of back pain were associated with the measure of anxious depression.…”

Section: Discussionmentioning

confidence: 68%

Back Pain without Disease or Substantial Injury in Children and Adolescents: A Twin Family Study Investigating Genetic Influence and Associations

et al. 2023

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This twin family study first aimed to investigate the evidence for genetic factors predicting the risk of lifetime prevalence of non-specific low back pain of at least three months duration (LBP (life)) and one-month current prevalence of thoracolumbar back pain (TLBP (current)) using a study of children, adolescents, and their first-degree relatives. Secondly, the study aimed to identify associations between pain in the back with pain in other regions and also with other conditions of interest. Randomly selected families (n = 2479) with child or adolescent twin pairs and their biological parents and first siblings were approached by Twins Research Australia. There were 651 complete twin pairs aged 6–20 years (response 26%). Casewise concordance, correlation, and odds ratios were compared for monozygous (MZ) and dizygous (DZ) pairs to enable inference about the potential existence of genetic vulnerability. Multivariable random effects logistic regression was used to estimate associations between LBP (life) or TLBP (current) as an outcome with the potentially relevant condition as predictors. The MZ pairs were more similar than the DZ pairs for each of the back pain conditions (all p values < 0.02). Both back pain conditions were associated with pain in multiple sites and with primary pain and other conditions using the combined twin and sibling sample (n = 1382). Data were consistent with the existence of genetic influences on the pain measures under the equal environments assumption of the classic twin model and associations with both categories of back pain were consistent with primary pain conditions and syndromes of childhood and adolescence. which has research and clinical implications.

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Section: Discussionmentioning

confidence: 68%

Back Pain without Disease or Substantial Injury in Children and Adolescents: A Twin Family Study Investigating Genetic Influence and Associations

et al. 2023

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“…The pathophysiology of musculoskeletal pain is not completely unstated, though, irritation, fibrosis, tissue poverty, and neurotransmitters as well as neurosensory turbulences have been expected to be related to the musculoskeletal pain. 1 - 5 Various treatments such as opioids, nonsteroidal anti-inflammatory drugs, or corticosteroids are measured as the type of maintenance for the pre- and postoperative and neuropathic management of pain. 6 However, administration with long-term opioids for precancer pain is static contentious.…”

Section: Introductionmentioning

confidence: 99%

A Novel Fabrication of Dose-Dependent Injectable Curcumin Biocomposite Hydrogel System Anesthetic Delivery Method for Care and Management of Musculoskeletal Pain

2020

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Chronic musculoskeletal pain has biological, psychological, and social components. In this article, we have demonstrated the easily injectable nanocomposite carrier for the treatment of chronic musculoskeletal pain. Briefly, the curcumin (Cur) loaded with lipid nanocapsules (LNCs; Cur@LNCs) using the phase invasion method. The synthesized Cur@LNCs were characterized by using scanning electron microscopy, transmittance electron microscopy, and the size of the fabricated nanoparticles confirmed by dynamic light scattering analysis. The synthesized Cur@LNC injectable hydrogel shows excellent results in vivo in the rat model. We have examined the efficiency of the chronic constriction injury in the rat model and induced the pain using thermal paw withdrawal latency. The injectable hydrogels Cur@LNCs display a remarkable reduction in pain 7 days post administrations compared to the untreated group animals. This work could establish the preclinical candidate of the neuropathic pain response in the future.

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Preventing back pain in schools: a dual epidemiological and ergonomic approach

Antoun,

ABOU ZEID DAOU,

Pelayo

2024

Proceedings of the European Conference on Cognitive Ergonomics 2024

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Baseline musculoskeletal pain and impaired sleep related to school pressure influence the development of musculoskeletal pain in N = 107 adolescents in a 5-year longitudinal study

Abstract: Baseline musculoskeletal pain and impaired sleep related to school pressure influence the development of musculoskeletal pain in N=107 adolescents in a five-year longitudinal studyMusculoskeletal pain in adolescents and young adults 2

Cited by 3 publications

References 27 publications

Back Pain without Disease or Substantial Injury in Children and Adolescents: A Twin Family Study Investigating Genetic Influence and Associations

Back Pain without Disease or Substantial Injury in Children and Adolescents: A Twin Family Study Investigating Genetic Influence and Associations

A Novel Fabrication of Dose-Dependent Injectable Curcumin Biocomposite Hydrogel System Anesthetic Delivery Method for Care and Management of Musculoskeletal Pain

Preventing back pain in schools: a dual epidemiological and ergonomic approach

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