2012
DOI: 10.1016/j.adengl.2011.05.005
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Basic Concepts in Skin Biopsy. Part I

Abstract: The aim of these reviews is to describe the reasons for performing skin biopsy, to provide indications for the choice of area to be biopsied and the preparation of the sample, and to summarize the various complications of dermatologic surgery. In addition, we present a guide for selecting the biopsy technique based on the suspected diagnosis and on the area to be biopsied. Finally, the various artifacts that can complicate interpretation of results are described, together with the methods used to prevent their… Show more

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Cited by 14 publications
(13 citation statements)
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“…The biopsy of cutaneous tissue samples is an invasive technique, common in dermatological practice and used in the diagnosis and analysis of changes in human skin structures and in the evaluation of therapeutic protocols used in integumentary system disorders. 1,14,32,40,41 HRUS emerged in 1970, as a noninvasive and nonionizing method to differentiate and measure skin layers, to identify skin lesions, and to monitor the evolution of dermatological treatments noninvasively, with high-quality images. [25][26][27][28][29][30][31][32]34,[36][37][38] Recent HRUS techniques using frequencies between 20 and 100 MHz are able to study the dermis and epidermis, to visualize the superficial structures of the integumentary system, and to identify dermal lesions.…”
Section: Discussionmentioning
confidence: 99%
“…The biopsy of cutaneous tissue samples is an invasive technique, common in dermatological practice and used in the diagnosis and analysis of changes in human skin structures and in the evaluation of therapeutic protocols used in integumentary system disorders. 1,14,32,40,41 HRUS emerged in 1970, as a noninvasive and nonionizing method to differentiate and measure skin layers, to identify skin lesions, and to monitor the evolution of dermatological treatments noninvasively, with high-quality images. [25][26][27][28][29][30][31][32]34,[36][37][38] Recent HRUS techniques using frequencies between 20 and 100 MHz are able to study the dermis and epidermis, to visualize the superficial structures of the integumentary system, and to identify dermal lesions.…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, since it performs per block wavelet transformation, blank blocks can be easily discarded so as to get more precise representations for irregular regions. We regard this feature extraction method potentially close to the intuition presented in many famous dermatology literatures [7][8] [9].…”
Section: B Region Feature Extractionmentioning
confidence: 98%
“…The second step is skin biopsy image analysis [8]. It is accepted that the second step is a complement of the first one [9] [10], in case that doctor has less confidence or even can't make decision only by inspecting skin surface. Skin biopsy image analysis can provide further information about the morbid condition that under the skin surface at in a microscopic vision [9] [11].…”
Section: Introductionmentioning
confidence: 99%
“…[4] In skin diseases that manifest with multiple lesions, once the physician performs complete physical examination of the patient along with a complete history he/she will choose the lesion to perform the biopsy. He/she will observe the most recent lesions, the most representative ones, in which no treatment was done, medically indicated or not, and if it is an evidence of more than one type of elementary lesion, he/she will decide to make as number of biopsies as types of lesions are present.…”
Section: Introductionmentioning
confidence: 99%