Basic Considerations in HPLC Method Development of Chiral Compounds

Ahuja, Satinder

doi:10.1002/9780470608661.ch3

Chiral Separation Methods for Pharmaceutical and Biotechnological Products 2010

DOI: 10.1002/9780470608661.ch3

|View full text |Cite

Basic Considerations in HPLC Method Development of Chiral Compounds

Satinder Ahuja¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Study on the Enantioselective Separation, Dissipation, and Residue of Chiral Fenpropathrin in Vegetables by Supercritical Fluid Chromatography-Tandem Mass Spectrometry (SFC-MS/MS)

Wang,

Liu

et al. 2024

J. Agric. Food Chem.

View full text Add to dashboard Cite

Chiral fenpropathrin is a widely used pyrethroid insecticide. A fast supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS) method was developed for the enantioselective study of fenpropathrin in five kinds of vegetables. The enantioseparation could be completed in 2 min, and the recoveries were 75.5−107.7% with RSDs of ≤15.2%. The dissipation halflives of R-fenpropathrin and S-fenpropathrin were 2.32−3.62 days and 1.89−3.56 days, respectively. The dissipation of fenpropathrin was the fastest in cucumbers and the slowest in celery cabbage. R-Fenpropathrin was preferentially dissipated in celery and cucumber, which was opposite in lettuce and pakchoi. The final residues of rac-fenpropathrin in celery cabbage, pakchoi, and lettuce were a little above the European Union's maximum residue limits (MRLs) but less than the China's MRLs. The acute and chronic dietary intake risks of rac-fenpropathrin for all age groups were acceptable. The results would provide a basis for the rational application and risk assessment of fenpropathrin.

show abstract

Study on the Enantioselective Separation, Dissipation, and Residue of Chiral Fenpropathrin in Vegetables by Supercritical Fluid Chromatography-Tandem Mass Spectrometry (SFC-MS/MS)

Wang,

Liu

et al. 2024

J. Agric. Food Chem.

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Basic Considerations in HPLC Method Development of Chiral Compounds

Cited by 1 publication

References 16 publications

Study on the Enantioselective Separation, Dissipation, and Residue of Chiral Fenpropathrin in Vegetables by Supercritical Fluid Chromatography-Tandem Mass Spectrometry (SFC-MS/MS)

Study on the Enantioselective Separation, Dissipation, and Residue of Chiral Fenpropathrin in Vegetables by Supercritical Fluid Chromatography-Tandem Mass Spectrometry (SFC-MS/MS)

Contact Info

Product

Resources

About