Basic dihydromorphanthridinones with anticonvulsant activity

Waring, W. Stephen; Whittle, B. A.

doi:10.1111/j.2042-7158.1969.tb08305.x

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1977

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Cited by 6 publications

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Anticonvulsants

Scott¹

2003

Burger's Medicinal Chemistry and Drug Discovery

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This chapter reports on the current and prospective anticonvulsant agents: their chemical structures, chemical names, pharmacokinetic parameters, and proposed mechanism(s) of action. Theoretical principles on structure‐activity development are presented as well as a brief explanation of animal testing to predict anticonvulsant activity. A hypothetical anticonvulsant model is presented that, within limits, is useful in elucidating the spatial/structural requirements for anticonvulsant activity against generalized epilepsy.

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