Basicities and structures of 2H,6H-2,6-dimethyl-4-amino-1,3,5-dithiazine and its N-acyl derivatives

Cyclothiomethylation of primary amines with formaldehyde and hydrogen sulfide to nitrogen- and sulfur-containing heterocycles (review)

“…Of special interest and promise among the various methods for the production of 1,3,5-dithiazinanes [23][24][25][26][27][28][29][30][31][32][33][34] is the simple and convenient method based on the multicomponent reaction of readily obtainable amines, formaldehyde, and H 2 S. This reaction, discovered by Wohl [23] more than 100 years ago, was not properly developed, and the few published data in a number of cases contain contradictory information.…”