Basilingual Xanthoma

Pérez-Plasencia, Daniel; Guerra-Jiménez, Gloria; Montenegro-Damaso, Társila; Ramos‐Macías, Ángel

doi:10.1016/j.otoeng.2011.06.006

Cited by 1 publication

(3 citation statements)

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“…In the present study, the second two lesions were detected only a short time after the first, indicating that endoscopists may miss many pharyngeal xanthomas during endoscopy because they are not familiar with the lesions' endoscopic appearance. It is not clear whether the minute pharyngeal xanthomas detected in the present study will develop into larger symptomatic lesions like those described in a previous report [2]. Nonetheless, the present study described the endoscopic findings of pharyngeal xanthomas.…”

Section: Discussioncontrasting

confidence: 70%

“…xanthomatosis with epiglottic and basilingual involvement and dyslipidemia has been reported [2]. The lesion was a protrusion of more than 3 cm that caused oropharyngeal foreign body sensation and dysphagia.…”

Section: Discussionmentioning

confidence: 99%

“…Xanthomas are non-neoplastic lesions that result from the accumulation of foamy histiocytes. They are characteristically found in the oral cavity and genital skin [1], although several reports have also described pharyngeal xanthomas, which are considered rarer [2]. In fact, most pharyngeal xanthomas occur in the context of the systemic disease xanthoma disseminatum [3][4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Sporadic Minute Pharyngeal Xanthomas Detected Incidentally During Esophagogastroduodenoscopy: A Case Series

Hamada

Takeuchi

Kubo

et al. 2018

Head and Neck Pathol

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Pharyngeal xanthomas are considered rare, and no reports have described their endoscopic appearance under magnifying or image-enhanced endoscopy. We report three cases of asymptomatic sporadic pharyngeal xanthoma that were detected incidentally during routine esophagogastroduodenoscopy. All the patients were men and had a solitary lesion of about 1 mm in size. Two of the lesions were located in the oropharynx, while one was in the hypopharynx. Non-magnifying endoscopy showed yellowish lesions, and magnifying endoscopy showed an aggregation of minute yellowish nodules with tortuous microvessels on their surface. Histopathological examination revealed foam cells filling the intraepithelial papillae. The foam cells were strongly immunopositive for cluster of differentiation (CD) 68. Immunohistochemical staining for CD34 showed intrapapillary capillaries around the foam cells. This characteristic magnifying endoscopic appearance corresponded to the histopathological findings of pharyngeal xanthomas. The present cases reveal the relationship between the endoscopic appearance and histopathological findings of pharyngeal xanthomas.

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Section: Discussioncontrasting

confidence: 70%

Section: Discussionmentioning

confidence: 99%