“…We included a wide range of covariates in the analyses as potential confounders based on prior literature. 8 , 9 , 12 , 18 , 21 Information on sex, age, hypertension, diabetes mellitus, smoking habit, alcohol intake, family structure, social participation, depressive symptoms, cognitive function, instrumental activities of daily living (IADL), educational attainment, and equivalent income was obtained from a self-administered questionnaire. Smoking habit and alcohol intake were classified into the following three categories: current, ever, and never.…”