BATO complexes derived from dimethoxy dioximes: Synthesis, characterization and biodistribution

The decrease in uptake observed with verapamil and diltiazem, the increase with Bay K 8644, and the lack of effect with nifedipine suggest that TcN-NOET binds to L-type calcium channels in the open configuration, without entering cardiomyocytes. The kinetics of TcN-NOET accumulation and retention are slow, and the mechanism for cellular uptake is not energy-dependent. From a clinical point of view, the effect of concurrent treatment by calcium inhibitors on myocardial binding of TcN-NOET should be taken into account.

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BATO complexes derived from dimethoxy dioximes: Synthesis, characterization and biodistribution

Cited by 2 publications

References 15 publications

Recent applications of high-performance liquid chromatography to the analysis of metal complexes

Recent applications of high-performance liquid chromatography to the analysis of metal complexes

Cellular Uptake Mechanisms of ^99m TcN-NOET in Cardiomyocytes From Newborn Rats

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BATO complexes derived from dimethoxy dioximes: Synthesis, characterization and biodistribution

Cited by 2 publications

References 15 publications

Recent applications of high-performance liquid chromatography to the analysis of metal complexes

Recent applications of high-performance liquid chromatography to the analysis of metal complexes

Cellular Uptake Mechanisms of 99m TcN-NOET in Cardiomyocytes From Newborn Rats

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Product

Resources

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Cellular Uptake Mechanisms of ^99m TcN-NOET in Cardiomyocytes From Newborn Rats