Battery Ingestion Leading to Bilateral Vocal Cord Paresis

Patel, Seraphim; Hıllel, Allen D.; Perkins, Jonathan A.

doi:10.1001/jamaoto.2013.1825

Cited by 11 publications

(10 citation statements)

References 7 publications

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“…Injuries and sequelae from inadvertent battery ingestion include vocal cord paralysis, esophageal strictures, esophageal perforation, tracheoesophageal fistula, and aortoesophageal fistula leading to death (1,(5)(6)(7)(8). It has been recognized for more than 30 y that esophageal impaction is associated with the most severe morbidity (7).…”

mentioning

confidence: 99%

Simple battery armor to protect against gastrointestinal injury from accidental ingestion

Laulicht

Traverso

Deshpande

et al. 2014

Proc. Natl. Acad. Sci. U.S.A.

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Inadvertent battery ingestion in children and the associated morbidity and mortality results in thousands of emergency room visits every year. Given the risk for serious electrochemical burns within hours of ingestion, the current standard of care for the treatment of batteries in the esophagus is emergent endoscopic removal. Safety standards now regulate locked battery compartments in toys, which have resulted in a modest reduction in inadvertent battery ingestion; specifically, 3,461 ingestions were reported in 2009, and 3,366 in 2013. Aside from legislation, minimal technological development has taken place at the level of the battery to limit injury. We have constructed a waterproof, pressure-sensitive coating, harnessing a commercially available quantum tunneling composite. Quantum tunneling composite coated (QTCC) batteries are nonconductive in the low-pressure gastrointestinal environment yet conduct within the higher pressure of standard battery housings. Importantly, this coating technology enables most battery-operated equipment to be powered without modification. If these new batteries are swallowed, they limit the external electrolytic currents responsible for tissue injury. We demonstrate in a large-animal model a significant decrease in tissue injury with QTCC batteries compared with uncoated control batteries. In summary, here we describe a facile approach to increasing the safety of batteries by minimizing the risk for electrochemical burn if the batteries are inadvertently ingested, without the need for modification of most battery-powered devices.coin cell battery ingestion | battery-induced injury | ingestion of foreign bodies | button battery safety | esophageal injury

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mentioning

confidence: 99%

Simple battery armor to protect against gastrointestinal injury from accidental ingestion

Laulicht

Traverso

Deshpande

et al. 2014

Proc. Natl. Acad. Sci. U.S.A.

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“…[36] Zn/AgO batteries offer comparable energy densities,b ut exhibit significant risk in the case of device retention and rupture including exposure to toxic metals and caustic electrolytes. [36] Zn/AgO batteries offer comparable energy densities,b ut exhibit significant risk in the case of device retention and rupture including exposure to toxic metals and caustic electrolytes.…”

Section: Primary Batteriesmentioning

confidence: 99%

“…Primary cell batteries continue to serve as the standard choice for on-board energy supplies.L ithium-ion batteries offer limited utility as power supplies for ingestible electromechancial systems due to safety concerns. [36] Zn/AgO batteries offer comparable energy densities,b ut exhibit significant risk in the case of device retention and rupture including exposure to toxic metals and caustic electrolytes. These risks can be managed by reducing device dimensions, improving the resilience of packaging,o ro ther innovative approaches.…”

Section: Primary Batteriesmentioning

confidence: 99%

Advances in Materials and Structures for Ingestible Electromechanical Medical Devices

Bettinger

2018

Angew Chem Int Ed

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Ingestible biomedical devices that diagnose, prevent, or treat diseases has been a dream of engineers and clinicians for decades. The increasing apparent importance of gut health on overall well-being and the prevalence of many gastrointestinal diseases have renewed focus on this emerging class of medical devices. Several prominent examples of commercially successful ingestible medical devices exist. However, many technical challenges remain before ingestible medical devices can achieve their full clinical potential. This Minireview summarizes recent discoveries in this interdisciplinary topic including novel materials, advanced materials processing techniques, and select examples of integrated ingestible electromechanical systems. After a brief historical perspective, these topics will be reviewed with a dedicated focus on advanced functional materials and fabrication strategies in the context of clinical translation and potential regulatory considerations. Future perspectives, challenges, and opportunities related to ingestible medical devices will also be summarized.

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“…[36] Zn/AgO-Batterien bieten vergleichbare Energiedichten, zeigen jedoch signifikante Risiken bei Retention oder Ruptur,z .B.d urch Freisetzung von toxischen Metallen und ätzenden Elektrolyten. [36] Zn/AgO-Batterien bieten vergleichbare Energiedichten, zeigen jedoch signifikante Risiken bei Retention oder Ruptur,z .B.d urch Freisetzung von toxischen Metallen und ätzenden Elektrolyten.…”

Section: Primärbatterienunclassified

“…Primärzellbatterien sind noch immer die Standardwahl fürd ie bordeigene Energieversorgung.L ithiumionen-Batterien kommen aufgrund von Sicherheitsbedenken nur bedingt als Energieversorgung fürs chluckbare elektromechanische Systeme in Frage. [36] Zn/AgO-Batterien bieten vergleichbare Energiedichten, zeigen jedoch signifikante Risiken bei Retention oder Ruptur,z .B.d urch Freisetzung von toxischen Metallen und ätzenden Elektrolyten. Diese Risiken kçnnen durch die Verkleinerung der Gerätedimensionen kontrolliert werden, ebenso auch durch die Erhçhung der Widerstandsfähigkeit des Packmaterials oder andere innovative Herangehensweisen.…”

Section: Primärbatterienunclassified

Materialien und Strukturen für schluckbare elektromechanische medizinische Funktionseinheiten

Bettinger

2018

Angewandte Chemie

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Schluckbare Biomedizinprodukte diagnostizieren, verhindern und behandeln ein breites Spektrum von Krankheiten und waren über Jahrzehnte der Traum von Ingenieuren und Klinikern. Der steigende Stellenwert der Darmgesundheit für das allgemeine Wohlbefinden sowie die Prävalenz vieler gastrointestinaler Erkrankungen haben die Aufmerksamkeit auf diese aufstrebende Klasse medizinischer Hilfsmittel neu geweckt. Es gibt mehrere prominente Beispiele von kommerziell erfolgreichen, schluckbaren Medizinprodukten. Dennoch bleiben viele technische Herausforderungen zu lösen, bevor schluckbare Medizinprodukte ihr volles klinisches Potenzial ausschöpfen können. Dieser Kurzaufsatz fasst neuste Entdeckungen in diesem interdisziplinären Gebiet zusammen, einschließlich neuartiger Materialien, moderner Verarbeitungstechniken für Materialien und ausgewählter Beispiele integrierter schluckbarer elektromechanischer Systeme. Nach einer kurzen historischen Betrachtung werden diese Themen mit einem speziellen Fokus auf modernen Funktionsmaterialien und Herstellungsstrategien im Kontext der klinischen Translation und potenzieller regulatorischer Überlegungen diskutiert. Zukünftige Perspektiven, Herausforderungen und Chancen des Gebiets werden ebenfalls zusammengefasst.

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Battery Ingestion Leading to Bilateral Vocal Cord Paresis

Abstract: Disk battery ingestion has the potential for recurrent laryngeal nerve damage and vocal cord paralysis. Expeditious battery removal and long-term care are crucial for successful ingestion management, as ingestion complications can be significant.

Cited by 11 publications

References 7 publications

Simple battery armor to protect against gastrointestinal injury from accidental ingestion

Simple battery armor to protect against gastrointestinal injury from accidental ingestion

Advances in Materials and Structures for Ingestible Electromechanical Medical Devices

Materialien und Strukturen für schluckbare elektromechanische medizinische Funktionseinheiten

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