Bazı Bitkisel Yağların Zebra Balıklarında Anestezik Rolü

Abstract

Anesthetics have been important in ornamental fishes for transport and restriction of behaviors as well as for surgical applications and studies in science. Also, more economical and appropriate anesthetics can be common choice for these stiuations. In the study, a total of two hundred and fifty two zebrafish (forty two females and forty two males in each group) divided in three groups were studied as group A (Anise oil); group T (Thyme oil); group M (Mint oil). Anesthesia intake and lethal dose values were determined by following the anesthetic entry and recovery times. There was no anesthetic effect in group A, while anesthetic effects occured in groups T and M in concentrations 1, 5, 10, 20 and 30 mg/l. Similarity was found in groups T and M in terms of anesthesia entry and recovery times (P>0.05). Nevertheless, no mortality occured in group M. However, 5mg/l tyme oil anesthesia was determined to cause 50% mortality in male fishes (group T). It was also observed that mint oil has an anesthetic effect on zebrafish with increasing doses determined by anesthesia entry and recorvery times (group M, P<0.05). Thereby, mint oil may be an alternative herbal anesthetic agent for zebrafish. However, further studies are neccessary to show the herbal anesthetics effect on ornamental fishes.

Efficacy of fennel (Foeniculum vulgare) and anise (Pimpinella anisum) essential oils as anaesthesics in common carp (Cyprinus carpio L. 1758)

“…For this reason, it has been observed that anise is not suitable for anaesthesia in carp. Similarly, Seyidoglu and Yagcılar ( 2020 ) reported that anise at concentrations of 0.1–30 mg L −1 did not show an anaesthetic effect and caused mortality in zebrafish.…”

“…In the selection criteria of anaesthetics, induction and recovery time of anaesthesia are important (Martins et al 2019 ). Anaesthetics should be effective in low concentrations and have no toxic effect on fish (Seyidoglu and Yagcılar 2020 ). Therefore, the search for natural anaesthetic agents that are reliable and effective in fish has increased in recent years.…”

“…Therefore, the search for natural anaesthetic agents that are reliable and effective in fish has increased in recent years. Previous studies have investigated effects of plant essential oils as effective, safe and inexpensive new anaesthetics (Inoue et al 2003 ; Velisek et al 2005 ; Seyidoglu and Yagcılar 2020 ).…”

“…Ugur ( 2019 ) reported that fennel essential oil showed an anaesthetic effect on rainbow trout. Anise essential oil has been demonstrated anaesthetic effect on zebrafish (Seyidoglu and Yagcılar 2020 ). In previous studies, different plant essential oils and active components have been studied as anaesthetic in common carp (Roohi and Imanpoor 2015 ; Mirghaed et al 2016 ; Mazandarani and Hoseini 2017 ; Mazandarani et al 2017 ; Rakhshani et al 2018 ; Khumpirapang et al 2018 ; Yousefi et al 2018a , 2018b ; Al-Niaem et al 2019 ; Krasteva et al 2021 ; Metin et al 2022 ).…”

Zebrafish models for the evaluation of essential oils (EOs): A comprehensive review

“…And different nanoformulations of EOs extracted from Alpinia galanga and Aeollanthus suaveolens were also evaluated for organ distribution properties and anesthetic activity in zebrafish using comparable techniques and indicators (de Oliveira Ferraz et al, 2020;Khumpirapang et al, 2021). Furthermore, recovery time served as a crucial metric for assessing the anesthetic efficacy of various EOs such as anise oil, thyme oil, and mint oil (Seyidoglu and Yagcilar, 2020), and EOs derived from Cuminum cyminum (Khosravanizadeh et al, 2020), Acmella oleracea, Piper alatabaccum (Leite et al, 2022). Greater amounts of serum could be collected and lower serum levels of cortisol were present in fish euthanized with clove oil (0.1%) compared with an equipotent dose of MS222 (7.8 mM).…”