Autonomist Marxist ideas and concepts are resurgent and, with their latent spatiality, are well placed to contribute to radical geographical debates. In particular, the methodology of ‘class composition’ analysis provides a rigorous, materialist critique of transforming capitalist social relations. This paper first provides vital historical–theoretical context from the milieu of Italian Operaismo, before emphasising the value of autonomist Marxist analyses of three contemporary geographical frontiers: labour process, migration, and social reproduction. It ultimately argues that the laudable motivations of the autonomous geographies project, explored in this very journal, would be better served through an explicitly materialist autonomist geography.