Present study addresses the role of major platedriving forces, particularly the slab pull and slab resistive forces, for the generation of 26 December 2004 M w [ 9.0 off Sumatra megathrust earthquake. Major controls on the plate-driving forces are normally visualized through age, speed, and average dip of the slab during subduction. Wide variation in age, plate obliquity, stress obliquity, subduction rate, dip angle, and flexing depth of the subducting oceanic lithosphere between Andaman and Sumatra thus allowed us for quantitative evaluation of the slab pull (F SP ) and slab resistive (F SR ) forces in three well-defined sectors (I, II and III). Computed values of these forces in the three sectors: (1) F SP = 1.29 9 10 13 N/m, F SR = 1.41 9 10 13 N/m; sector I, (2) F SP = 2.10 9 10 13 N/m, F SR = 1.13 9 10 13 N/m; sector II, and (3) F SP = 2.08 9 10 13 N/m, F SR = 2.72 9 10 13 N/m; sector III clearly suggest a spatial variation of stress regime in the subducting oceanic lithosphere. Excess F SR in sectors I and III are interpreted as the causative forces behind the triggering of major seismic energy bursts near Sumatra and Andaman on 26 December 2004. A gap of minimum seismic energy burst near Great Nicobar possibly was controlled by the excess of F SP in sector II. This study further advocates that the cyclic stress, resulted from unbalanced component of slab resistive force, had a definite control on the occurrence of 2004 off Sumatra megathrust earthquake around the flexing zone of the subducting lithosphere.