Becker's nevus syndrome revisited

Síndrome do nevo de Becker: relato de caso

“…2 The proportion between the male and female sexes has been already described as 2:1. 4,6 However, Happle and Koopman believe that the prevalence is the same between sexes and suggest that the disease among women as it is more discrete is underdiagnosed. 3 On average, lesions occur around eight years of age and become more evident in puberty.…”

“…The dermis can present a superficial and perivascular lympho-histiocytic infiltrate and melanophages can be seen in the papillary dermis. 5,6 In some cases it is found hyperplasia of smooth muscle fibers arranged in a disorganized way in the reticular dermis, Baeta IGR, Viotti CV, Pereira ACF, Costa SR Jr, Bittencourt FV corresponding to a hamartoma. 4,7 The majority of the authors attribute an spectral concept to the Becker's nevus and to the smooth muscle hamartoma.…”

“…4,7 The majority of the authors attribute an spectral concept to the Becker's nevus and to the smooth muscle hamartoma. [6][7][8][9] The etiopathogenesis is not clear yet. The distribution of the lesions reflects a mosaicism pattern.…”

“…The muscleskeletal abnormalities manifest themselves with scoliosis, pectus excavatum, pectus carinatum and vertebral dysfunctions and the maxillofacial with facial asymmetry, absence of central incisors and canines. 6 As for women, the most frequently found abnormality is the ipsilateral mammary hypoplasia, which can have its pathogenesis explained by the increase in the number of androgen-receptors in the fibroblasts of the affected areas. 6,10 It can affect only the areola, the nipple or the entire breast and it is not exclusive of the female sex.…”

“…Becker´s nevus syndrome is associated with other cutaneous anomalies, musculoskeletal or maxillofacial. 3,6 In women the most commonly found anomaly is the ipsilateral mammary hypoplasia. 6 …”