Bedeutung der Untersuchung fetaler Augen

Abstract

The investigation of fetal eyes is a subspecialty, which is performed by only a few ophthalmic pathologists and pathologists in specialized centers. If a certain fetal syndrome is suspected, the fetal eyes should be removed and submitted for ophthalmic pathological investigation in a specialized center. This can provide additional diagnostic information allowing a final classification of a syndrome and the comprehensive genetic counselling of parents with respect to future pregnancies. This article provides an overview of the histopathological findings in fetal eyes, which are of particular relevance for the pediatric pathological autopsy. In addition, the basic points of ocular development, the preparation of fetal eyes and frequent artifacts are presented.

Goldstandard Ophthalmopathologie – noch zeitgemäß?

“…Die ophthalmopathologische Aufarbeitung fetaler Augen [49] führte neben weiteren Erkenntnissen hinsichtlich der physiologischen Entwicklung [50] auch zur Charakterisierung von Artefakten [51], die in verschiedenen okulären Strukturen die Beurteilung erschweren und bei der Linse sogar eine Katarakt vortäuschen können (▶ Abb. 14) [52].…”