Bedroom Allergen Exposure Beyond House Dust Mites

Salo, Päivi M.; Cohn, Richard D.; Zeldin, Darryl C.

doi:10.1007/s11882-018-0805-7

Cited by 13 publications

(3 citation statements)

References 206 publications

(293 reference statements)

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“…The incidence of allergy to common allergens... the high contribution of mites in the development of bronchial asthma, the significant influence of cockroach allergen has also been demonstrated [57,58].…”

Section: Discussionmentioning

confidence: 99%

The Incidence of Allergy to Common Allergens Based on a Retrospective Analysis

Czarny-Działak¹,

Działak²,

Wójcik³

et al. 2021

hpc

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Authors' contribution Wkład autorów:A. Study design/planning zaplanowanie badań B. Data collection/entry zebranie danych C. Data analysis/statistics dane -analiza i statystyki D. Data interpretation interpretacja danych E. Preparation of manuscript przygotowanie artykułu F. Literature analysis/search wyszukiwanie i analiza literatury G. Funds collection zebranie funduszy SummaryBackground. The aim of this work was to find out which of the aeroallergens most often cause positive skin prick tests in the population with allergic diseases. Depending on the type of allergens, exposure to them can aggravate asthma symptoms and cause allergic conjunctivitis and allergic rhinitis. Material and methods. A group of 100 people between 18 and 78 years of age were included in the study. The average age was 45.8 years. There were 34 men and 66 women in the group. All patients were allergy clinic patients. The results of point skin tests for the basic aeroallergen panel were analyzed in this study and summarized using descriptive statistics. Results. Sixty subjects had positive tests for dust mites. Most subjects were allergic to two allergens. Monovalent allergy was found in 10 subjects. Multivalent allergy was predominant, but tended to involve relatively few allergens. Conclusions. The results obtained may be due to year-round exposure to the house dust mite allergen. Prolonged allergen exposure translates into more frequent immune responses and greater clinical response of patients, which is manifested by allergic rhinitis and/or bronchial asthma or allergic conjunctivitis. Due to the small patient population studied, this subject requires further analysis.

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Section: Discussionmentioning

confidence: 99%

The Incidence of Allergy to Common Allergens Based on a Retrospective Analysis

Czarny-Działak¹,

Działak²,

Wójcik³

et al. 2021

hpc

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“…The indoor occurrence of Alternaria, Aspergillus, Candida, Cladosporium and Penicillium has been associated with increased asthma and asthma epidemics [16][17][18][19]. Symptoms of 4.6 of the total of 21.8 million asthmatics in the USA are caused by indoor dampness and mould, with an annual cost of 3.5 billion dollars.…”

Section: Discussionmentioning

confidence: 99%

Fungi in Public Heritage Buildings in Poland

Kwaśna¹,

Kuberka²

2020

Pol. J. Environ. Stud.

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With the prevalence of asthma increasing worldwide in recent decades there is a growing need to determine the diversity and spatiotemporal dynamics of airborne microbes in indoor environments. Hence, the aims of this study were to detect and identify fungi present in public heritage buildings (libraries, museums, churches) in Poland. Samples of indoor dust and biofilm were collected from 60 areas in 10 such buildings (mostly in urban environments) in different seasons in 2008-2011. Mycological analysis was based on the culture-dependent method using 2% MEA and SNA. In 300 samples there were at least 160 fungal species belonging to more than 70 genera. The most common were Acremonium,

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“…Salivary-origin Fel d 1 is transferred from saliva to cats' hair when cats groom themselves and transferred to the environment on shed hair and dander. All cats produce Fel d 1 regardless of breed, age, hair (length, color or pattern), sex (male or female; neutered or intact), housing (indoors vs. outdoors), or body weight; there are no truly allergen-free or hypoallergenic cats (3,(5)(6)(7)(8)(9)(10). Fel d 1's function for the cat has not been definitively determined, but proposed roles include pheromone/chemical signaling, epithelial defense, lipid regulation and immunoregulation (11)(12)(13)(14)(15)(16)(17)(18).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of anti-Fel d 1 IgY ingredient for pet food on growth performance in kittens

Hedrick,

Matulka,

Conboy-Schmidt

et al. 2024

Front. Vet. Sci.

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IntroductionThe domestic cat (Felis catus) is one of the most common pets. Worldwide, approximately one in five adults are sensitive to cat allergens. The major cat allergen is the secretoglobulin Fel d 1, which is primarily produced in the salivary and sebaceous glands. Chickens produce IgY antibodies, which are similar in structure to mammalian IgG. When chickens are exposed to Fel d 1, anti-Fel d 1-specific IgY (AFD1) is produced and is naturally concentrated in egg yolk. The aim of this study was to evaluate the tolerability, effects on growth and food consumption, and potential adverse effects of a chicken egg product ingredient containing AFD1 in kittens.MethodsThis was a blinded, controlled study. Twenty-seven (27) eight-week old kittens were randomly assigned to three feeding groups containing 0 ppm AFD1 (Group 0), 8 ppm AFD1 (Group 1), and 16 ppm AFD1 (Group 2) for 84 days. Veterinary exams and bloodwork were performed on Day 42 and Day 84, and body weight and body condition score (BCS) were monitored weekly.ResultsThroughout the study, there were no signs of nutritional deficiency or adverse clinical events in any of the subjects. Administration of a chicken egg product ingredient containing AFD1 in the diet (whether in coating or combination of coating and top dress) had no significant effect on body weight nor food consumption, and all subjects maintained a healthy Body Condition Score (BCS) throughout the study. Moreover, there were no biologically significant differences in the mean clinical chemistry and hematology parameters.DiscussionThis study demonstrated that a diet formulated to contain up to 16 ppm AFD1, included in the coating and the top-dress of dry kitten food, was well tolerated, promoted adequate growth, and exhibited no adverse effects.

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Bedroom Allergen Exposure Beyond House Dust Mites

Cited by 13 publications

References 206 publications

The Incidence of Allergy to Common Allergens Based on a Retrospective Analysis

The Incidence of Allergy to Common Allergens Based on a Retrospective Analysis

Fungi in Public Heritage Buildings in Poland

Evaluation of anti-Fel d 1 IgY ingredient for pet food on growth performance in kittens

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