Background: Engaging in perspective-taking often has positive outcomes for both healthcare providers and patients. Perspective-taking by healthcare providers has been linked to increased patient satisfaction and compliance, patients' positive perceptions of healthcare providers' interpersonal skills, and a reduction in judgmental attitudes toward individuals who engage in health-risk behaviors. The positive outcomes that are associated with perspective-taking are often highlighted in the literature. However, less discussed are the negative outcomes.Aim: This paper discusses the positive and negative outcomes associated with perspective-taking and presents potential methods for mitigating negative outcomes.Conclusion: When designing and implementing perspective-taking interventions, educators and researchers should consider potential negative intervention outcomes and strategies to attenuate these outcomes. K E Y W O R D S communication, education, empathy, nurse-patient relations, perspective-taking AUTHOR BIOGRAPHIES Lisa Hoplock, PhD, was a postdoctoral fellow at