Bedtimes and Blood Pressure: A Prospective Cohort Study of Mexican Adolescents

Jansen, Erica C.; Dunietz, Galit Levi; Matos-Moreno, Amilcar; Solano, Maritsa; Lazcano‐Ponce, Eduardo; Sánchez-Zamorano, Luisa María

doi:10.1093/ajh/hpz191

Cited by 28 publications

(16 citation statements)

References 30 publications

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“…Many studies have explored the association between sleep duration and BP. A A participant with earlier bedtime on a weekday also had a higher risk of elevated BP (risk ratio = 1.96; 95% CI =1.27, 3.01) (24), which was similar compared with our research. The biological mechanism of the relationship between sleep patterns and BP has not been clear yet.…”

Section: Discussionsupporting

confidence: 87%

Association Between Bedtime at Night and Systolic Blood Pressure in Adults in NHANES

Long

et al. 2021

Front. Med.

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Objectives: This study aimed to explore the association between bedtime at night and systolic blood pressure (SBP) in adults.Methods: We conducted a cross-sectional study composed of 7,642 individuals from the National Health and Nutrition Examination Survey (NHANES). Bedtime was defined as the response to the question: “What time do you usually fall asleep on weekdays or workdays?” SBP was taken using the average of all measured values. Multiple linear regression analyses were done to explore the relationship between bedtime and SBP.Results: The bedtime was changed from categorical variable to continuous variable for data analysis, and a significantly negative association was identified between bedtime and SBP (β, −0.23 [95% CI, −0.43, −0.02]). With the delay of bedtime, the SBP showed a gradual decrease trend, and it was dropped to the lowest at 0:00. After 0:00, the SBP was gradually increased with the delay of sleep time. The stratified analyses showed that in the female group, with the delay of bedtime, the range of SBP was decreased more obviously at 0:00. In the 18–45 year group, bedtime had little effect on SBP. Among ≥45 years old group, this trend was still the same. In the black group, an obvious downward trend was found at 22:00.Conclusion: With the delay of bedtime, the SBP had shown a gradual decrease trend, and it was dropped to the lowest at 0:00. After 0:00, the SBP was gradually increased with the delay of sleep time. Bedtime and SBP showed a U-shaped relationship.

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Section: Discussionsupporting

confidence: 87%

Association Between Bedtime at Night and Systolic Blood Pressure in Adults in NHANES

Long

et al. 2021

Front. Med.

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“…On the contrary to our results, in a study by Yan et al [ 37 ], a later bedtime (after midnight) was associated with an increased prevalence of diabetes (OR 1.446; 95% CI 1.107–1.888]. A U-shaped relationship between the prevalence of hypertension and bedtime was observed by Jansen et al [ 38 ]. The risk of hypertension was almost two-fold higher in those participants who went to bed before 9 p.m., as well as after 11 p.m., in comparison to those, who went to bed between 9 p.m. and 11 p.m. (RR 1.96; 95% CI 1.27–3.01; RR1.87; 95% CI 1.09–2.21, respectively) [ 38 ].…”

Section: Discussioncontrasting

confidence: 99%

“…A U-shaped relationship between the prevalence of hypertension and bedtime was observed by Jansen et al [ 38 ]. The risk of hypertension was almost two-fold higher in those participants who went to bed before 9 p.m., as well as after 11 p.m., in comparison to those, who went to bed between 9 p.m. and 11 p.m. (RR 1.96; 95% CI 1.27–3.01; RR1.87; 95% CI 1.09–2.21, respectively) [ 38 ]. Similarly, a U-shaped relationship between bedtime and health outcomes was observed in the global PURE study [ 8 ].…”

Section: Discussionmentioning

confidence: 78%

Sleep Duration and Bedtime in the PURE Poland Cohort Study and the Link with Noncommunicable Diseases

Zatońska

Basiak-Rasała

Połtyn–Zaradna

et al. 2021

IJERPH

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(1) Background: The objective was to investigate the association between sleep duration, bedtime, and noncommunicable diseases in the PURE Poland cohort study. (2) Methods: The baseline study was conducted in 2007–2010. The study group comprised 2023 adult inhabitants of urban and rural areas in Lower Silesia, Poland. The study protocol included questionnaires, blood pressure measurements, blood draws, and anthropometric measurements. Sleep duration and bedtime were self-reported. (3) Results: The median sleep duration of women was 30 min longer than men (8 h vs. 7.5 h; p = 0.001). The average time of sleep increased along with the age of the participants. A sleep duration of >8 h was more common in rural than in urban participants (40.2% vs. 27.1%; respectively; p < 0.001). The relative risk of diabetes, stroke, hypertension, cardiovascular diseases (CVD), and obesity was significantly higher in participants who went to bed between 6 p.m. and 10 p.m. in comparison to those who went to bed between 10 p.m. and 12 a.m. (RR 2.23, 95%CI 1.06–4.67; RR 2.52, 95%CI 1.28 to 4.97; RR 1.12, 95%CI 1.04–1.20; RR 1.36; 95%CI 1.1–1.68; RR 1.38; 95%CI 1.15–1.66, respectively). The relative risk of respiratory diseases was two-fold higher in those who went to bed after midnight in comparison to those who went to bed between 10 p.m. and 12 a.m. (RR 2.24; 95%CI 1.19–4.22). (4) Conclusions: In our study, an earlier bedtime was associated with a higher risk of diabetes, stroke, obesity, hypertension, and CVD.

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“…25 Jansen et al found that Mexican adolescents with a weekday bedtime later than 11pm had a 1·87 times higher risk of developing elevated BP than the participants with a bedtime between 9pm and 10pm, after accounting for sleep-related confounders. 26 In our study, however, the association between timing of sleep and CVD incidence remained robust even after additional adjustment for important CVD risk factors, such as hypertension, diabetes, BMI, and smoking.…”

Section: Discussioncontrasting

confidence: 62%

Accelerometer-derived sleep onset timing and cardiovascular disease incidence: a UK Biobank cohort study

Nikbakhtian¹,

Reed²,

Obika³

et al. 2021

Preprint

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Aims Growing evidence suggests that sleep quality is associated with cardiovascular risk. However, research in this area often relies upon recollection dependant questionnaires or diaries. Accelerometers provide an alternative tool for deriving sleep parameters measuring sleep patterns objectively. This study examines the associations between accelerometer derived sleep onset timing and cardiovascular disease (CVD). Methods and Results We derived sleep onset and waking up time from accelerometer data collected from 103,712 UK Biobank participants over a period of seven days. From this, we examined the association between sleep onset timing and CVD incidence using a series of Cox proportional hazards models. 3172 cases of CVD were reported during a mean follow-up period of 5.7 (±0.49) years. An age- and sex-controlled base analysis found that sleep onset time of 10:00pm-10:59pm was associated with the lowest CVD incidence. A fully adjusted model, additionally controlling for sleep duration, sleep irregularity, and established CVD risk factors, was unable to eliminate this association, producing hazard ratios of 1.24 (95% CI, 1.10-1.39; p<0.005), 1.12 (1.01-1.25; p=0.04), and 1.25 (1.02-1.52; p=0.03) for sleep onset <10:00pm, 11:00pm-11:59pm, and & ≥12:00am, respectively, compared to 10:00pm-10:59pm. Importantly, sensitivity analyses revealed this association was stronger in females, with only sleep onset <10:00pm significant for males. Conclusions Our findings suggest an independent relationship between sleep onset timing and risk of developing CVD, particularly for women. We also demonstrate the potential utility of collecting information about sleep parameters via accelerometry-capable wearable devices, which may serve as novel cardiovascular risk indicators.

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Bedtimes and Blood Pressure: A Prospective Cohort Study of Mexican Adolescents

Cited by 28 publications

References 30 publications

Association Between Bedtime at Night and Systolic Blood Pressure in Adults in NHANES

Association Between Bedtime at Night and Systolic Blood Pressure in Adults in NHANES

Sleep Duration and Bedtime in the PURE Poland Cohort Study and the Link with Noncommunicable Diseases

Accelerometer-derived sleep onset timing and cardiovascular disease incidence: a UK Biobank cohort study

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