Beet Root Juice: An Ergogenic Aid for Exercise and the Aging Brain

Petrie, Meredith Blair; Rejeski, W. Jack; Basu, Swati; Laurienti, Paul J.; Marsh, Anthony P.; Norris, James L.; Kim‐Shapiro, Daniel B.; Burdette, Jonathan H.

doi:10.1093/gerona/glw219

Cited by 11 publications

(7 citation statements)

References 39 publications

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“…Differences in the results might be due to the small sizes of the investigated groups (8–64 participants) [ 127 , 128 , 129 , 130 ]. In 2022, it was concluded that beetroot consumption is not important in this aspect [ 131 ].…”

Section: Influence Of Root Vegetables On Healthmentioning

confidence: 99%

Root Vegetables—Composition, Health Effects, and Contaminants

Knez

Kadac-Czapska

Dmochowska-Ślęzak

et al. 2022

IJERPH

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Root vegetables are known all over the world, but they are being less and less consumed by individuals. The main purpose of this article was to summarize the benefits, health effects, and threats associated with the consumption of carrot, celery, parsley, beetroot, radish, turnip, and horseradish. They are characterized by high nutritional value due to their richness in dietary fiber, vitamins, and minerals. One of their most important features is their high content of bioactive compounds, such as polyphenols, phenols, flavonoids, and vitamin C. These compounds are responsible for antioxidant potential. Comparison of their antioxidant effects is difficult due to the lack of standardization among methods used for their assessment. Therefore, there is a need for a reference method that would allow for correct interpretation. Moreover, root vegetables are characterized by several health-promoting effects, including the regulation of metabolic parameters (glucose level, lipid profile, and blood pressure), antioxidant potential, prebiotic function, and anti-cancer properties. However, due to the type of cultivation, root vegetables are vulnerable to contaminants from the soil, such as toxic metals (lead and cadmium), pesticides, pharmaceutical residues, microplastics, and nitrates. Regardless, the low levels of toxic substances present in root vegetables do not pose health risks to the average consumer.

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Section: Influence Of Root Vegetables On Healthmentioning

confidence: 99%

Root Vegetables—Composition, Health Effects, and Contaminants

Knez

Kadac-Czapska

Dmochowska-Ślęzak

et al. 2022

IJERPH

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“…In addition, the consistency of the SMC community increased after the dance intervention. Increased community consistency within this region has been shown to occur after exercise in older adults and is tied to positive outcomes (Petrie et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Improvisational Movement to Improve Quality of Life in Older Adults With Early-Stage Dementia: A Pilot Study

Thumuluri

Lyday

Babcock

et al. 2022

Front. Sports Act. Living

Self Cite

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Alzheimer's disease has profound effects on quality of life, affecting not only cognition, but mobility and opportunities for social engagement. Dance is a form of movement that may be uniquely suited to help maintain quality of life for older adults, including those with dementia, because it inherently incorporates movement, social engagement, and cognitive stimulation. Here, we describe the methods and results of the pilot study for the IMOVE trial (NCT03333837, www.clinicaltrials.gov), a clinical trial designed to use improvisational dance classes to test the effects of movement and social engagement in people with mild cognitive impairment (MCI) or early-stage dementia. The pilot study was an 8-week investigation into the feasibility and potential effects of an improvisational dance intervention on people with MCI or early-stage dementia (PWD/MCI) and their caregivers (CG). The pilot aimed to assess changes in quality of life, balance, mood, and functional brain networks in PWD/MCI and their CG. Participants were recruited as dyads (pairs) that included one PWD/MCI and one CG. Ten total dyads were enrolled in the pilot study with five dyads assigned to the usual care control group and five dyads participating in the dance intervention. The intervention arm met twice weekly for 60 min for 8 weeks. Attendance and quality of life assessed with the Quality of Life in Alzheimer's disease (QoL-AD) questionnaire were the primary outcomes. Secondary outcomes included balance, mood and brain network connectivity assessed through graph theory analysis of functional magnetic resonance imaging (fMRI). Class attendance was 96% and qualitative feedback reflected participants felt socially connected to the group. Increases in quality of life and balance were observed, but not mood. Brain imaging analysis showed increases in multiple brain network characteristics, including global efficiency and modularity. Further investigation into the positive effects of this dance intervention on both imaging and non-imaging metrics will be carried out on the full clinical trial data. Results from the trial are expected in the summer of 2022.

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“…The effects of potential interventions 236 including ketones, 169 MUFA, SFA, n-3 and n-6 PUFAs, 283 B vitamins, vitamin E, carotenoid, carotene and lycopene, 283 resveratrol, 284,285 cholesterol related lipids, 286 beetroot juice 287 225 Isoprostanes formed by free-radical-mediated peroxidation of PUFAs in response to inflammation are AD biomarkers, 226 though studies associate them with other dementias. 227 Novel metabolomic studies can reveal several potential AD biomarkers in urine, including DCAs and lysophospholipids.…”

Section: Functional Connectivity Fmrimentioning

confidence: 99%

Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias

Yassine

Self

Kerman

et al. 2022

Alzheimer's & Dementia

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Disturbances in the brain's capacity to meet its energy demand increase the risk of synaptic loss, neurodegeneration, and cognitive decline. Nutritional and metabolic interventions that target metabolic pathways combined with diagnostics to identify deficits in cerebral bioenergetics may therefore offer novel therapeutic potential for Alzheimer's disease (AD) prevention and management. Many diet-derived natural bioactive components can govern cellular energy metabolism but their effects on brain aging are not clear. This review examines how nutritional metabolism can regulate brain bioenergetics and mitigate AD risk. We focus on leading mechanisms of cerebral bioenergetic breakdown in the aging brain at the cellular level, as well as the putative causes and consequences of disturbed bioenergetics, particularly at the blood-brain barrier with implications for nutrient brain delivery and nutritional interventions. Novel therapeutic nutrition approaches including diet patterns are provided, integrating studies of the gut microbiome, neuroimaging, and other biomarkers to guide future personalized nutritional interventions.

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Beet Root Juice: An Ergogenic Aid for Exercise and the Aging Brain

Cited by 11 publications

References 39 publications

Root Vegetables—Composition, Health Effects, and Contaminants

Root Vegetables—Composition, Health Effects, and Contaminants

Improvisational Movement to Improve Quality of Life in Older Adults With Early-Stage Dementia: A Pilot Study

Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias

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