Beginning the trajectory to ESKD in adult life: albuminuria in Australian aboriginal children and adolescents

Kim, Siah; Macaskill, Petra; Hodson, Elisabeth M; Daylight, Jennifer; Williams, Rita; Kearns, Rachael; Vukasin, Nicola; Lyle, David; Craig, Jonathan C.

doi:10.1007/s00467-016-3429-y

Cited by 14 publications

(13 citation statements)

References 40 publications

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“…Likewise, there are reports on the prevalence of albuminuria (8.3% vs. 2.1%) in newborn infants with low birth weights when compared to normal-weight newborns [ 67 ]. Some studies also report a similar albuminuria prevalence in ethnic groups [ 66 ], even when others show differences in albuminuria levels in Australian aboriginal and non-aboriginal people [ 68 ]. It is important to emphasize that in the latter study, the difference observed in Australian aboriginal people is associated with obesity, which was already discussed previously.…”

Section: Resultsmentioning

confidence: 98%

Non-Traditional Risk Factors of Albuminuria in the Pediatric Population: A Scoping Review

Sierra-Díaz

Rosa

Lozano-Kasten

et al. 2017

IJERPH

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The presence of albumin in urine has been used for more than four decades as a marker of renal and cardiovascular damage. Most of the information on this marker is related to adults. The prevalence of albuminuria in the pediatric population has been reported as being 2.2–12.8% in some countries. Most research in this field is related to albuminuria and diseases, such as diabetes and hypertension. Using the methodology described by Arksey and O’Malley in 2005, a scoping review was carried out to show that the presence of albumin in urine in the pediatric population might be associated with environmental, demographic, congenital, infectious, and non-infectious factors. The information collected is supported by 74 references present in PubMed. The results reveal the multiple causes associated with albuminuria in the pediatric population. This information can be very useful for clinical practice by adding knowledge about albuminuria behavior in children.

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Section: Resultsmentioning

confidence: 98%

Non-Traditional Risk Factors of Albuminuria in the Pediatric Population: A Scoping Review

Sierra-Díaz

Rosa

Lozano-Kasten

et al. 2017

IJERPH

View full text Add to dashboard Cite

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“…Similarly, an Australian cross-sectional study with a sample of 975 children also reported a negative correlation between albuminuria and overweight or obesity [ 22 ]. Moreover, a prospective cohort study by Kim et al, involving 3418 children, discovered that the risk of albuminuria in children decreased as the BMI standard deviation score increased [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

Non-linear relationship between body roundness index and albuminuria among children and adolescents aged 8–19 years: A cross-sectional study

Qin,

Wei,

Chen

et al. 2024

PLoS ONE

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Introduction Obesity has been found to be correlated with numerous health issues, including an elevated risk of albuminuria in adults. However, this correlation is still controversial among children and adolescents, as several recent large-scale cross-sectional studies have observed a negative correlation between obesity and albuminuria. Our study aimed to investigate the link between the body roundness index (BRI) and albuminuria among children and adolescents, in order to further understand the correlation between obesity and albuminuria in this demographic. Methods We employed information from the National Health and Nutrition Examination Survey (NHANES) 1999–2010 for cross-sectional analysis. Weighted logistic regression was employed to explore the linear relationship between BRI and albuminuria, with subgroup analyses performed for more detailed insights. Weighted linear regression analysis was employed to explore the relationship between BRI and the urine albumin-creatinine ratio (UACR). Additionally, we applied smooth curve fitting to investigate their non-linear relationship and conducted threshold effect analysis to identify any turning point. Results In this study of 15,487 participants aged 8–19 years, multivariate logistic regression analysis revealed a significant negative correlation between BRI and albuminuria (OR = 0.616, 95%CI: 0.526–0.722). The relationship between BRI and UACR, as shown by multivariate linear regression analysis, was significantly inversely correlated (β: -5.424, 95%CI: -7.416 to -3.433). Furthermore, smooth curve fitting and threshold effect analysis showed a non-linear relationship between BRI and albuminuria, with a BRI inflection point identified at 2.906. Conclusions These findings of our study suggest a significant nonlinear negative association between BRI and the presence of albuminuria among children and teenagers, and maintaining an appropriate BRI may decrease the occurrence of albuminuria in this population.

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“…A prospective population-based cohort study in New South Wales -The Antecedents of Renal Disease in Aboriginal Children (ARDAC) Study, initiated in 2002, aimed to determine whether Aboriginal children have an increased risk of albuminuria in childhood, the ultimate goal being to identify factors that can reduce the incidence of Aboriginal CKD [7]. This large study did not show race to be associated with albuminuria, compared to female gender and lower birth weight which were found to associated with an increased risk of persistent albuminuria.…”

Section: Australia-aboriginal and Torres Strait Islandersmentioning

confidence: 99%

Kidney Health of Indigenous Children: Insights from Australia, Aotearoa New Zealand, and Canada

2022

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Purpose of Review This review seeks to highlight the common and unique factors that impact the kidney health of Indigenous children in Australia, Aotearoa New Zealand, and Canada with a particular interest on efforts to improve their kidney health outcomes and the framework to pursue future efforts. Recent Findings In the period since the adoption of the United Nations (UN) Declaration on the Rights of Indigenous People (UNDRIP) there has been a number of studies documenting poorer renal health outcomes and potential causes amongst Indigenous paediatric populations in Australia, Aotearoa New Zealand, and Canada. There is a shortage of studies that look at interventions to improve these outcomes. Summary Poorer kidney health outcomes amongst Indigenous children are rarely genetic and appear to be more related to societal inequities. Reported efforts to improve outcomes are few but have demonstrated the ability to make change and with sustained focus on reducing inequities there is hope to improve the renal health of Indigenous children.

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Beginning the trajectory to ESKD in adult life: albuminuria in Australian aboriginal children and adolescents

Cited by 14 publications

References 40 publications

Non-Traditional Risk Factors of Albuminuria in the Pediatric Population: A Scoping Review

Non-Traditional Risk Factors of Albuminuria in the Pediatric Population: A Scoping Review

Non-linear relationship between body roundness index and albuminuria among children and adolescents aged 8–19 years: A cross-sectional study

Kidney Health of Indigenous Children: Insights from Australia, Aotearoa New Zealand, and Canada

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