Behavior of atrial ectopic beats before and after pulmonary vein isolation in patients with atrial fibrillation: A reduction in the number and arrhythmogenicity of ectopic firings

Yamane, Teiichi; Date, Taro; Kanzaki, Yasuko; Inada, Keiichi; Matsuo, Seiichiro; Shibayama, Kentaro; Miyanaga, Satoru; Miyazaki, Hidekazu; Sugimoto, Kunihisa; Mochizuki, Seibu

doi:10.1016/j.hrthm.2006.08.023

Cited by 25 publications

(26 citation statements)

References 14 publications

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“…1 In a single study, the occurrence of PAC before and after RFA for AF was evaluated. 12 These results showed a generally high frequency of PAC before ablation procedure (12.8±10.7% of recorded heart beats during 24 hours) and a significant reduction after successful treatment. The reduction was shown to be progressive in the first 6 months after which time it stabilized.…”

Section: Discussionmentioning

confidence: 56%

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Atrial Ectopy Predicts Late Recurrence of Atrial Fibrillation After Pulmonary Vein Isolation

Gang

Nalliah

Lim

et al. 2015

Circ: Arrhythmia and Electrophysiology

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Background-Late recurrence of atrial fibrillation (AF) after radiofrequency ablation remains significant. Asymptomatic recurrence poses a difficult clinical problem as it is associated with an equally increased risk of stroke and death compared with symptomatic AF events. Meta-analyses reveal that no single preablation patient characteristic efficiently predicts these AF recurrences. This study aimed to evaluate the prognostic value of premature atrial complex (PAC) occurrence with regard to the risk of late AF recurrence after radiofrequency ablation. Methods and Results-The study cohort consisted of 124 patients with 7-day Holter recordings at 6 months post radiofrequency ablation for AF. No patients had AF recurrence before this time. Patients were followed-up every 6 months. Holter-detected PACs were defined as any supraventricular complexes occurring >30% earlier than expected.

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Section: Discussionmentioning

confidence: 56%

“…Some evidence suggests that successful PVI reduces the number of PAC. 12 The aim of this study was to assess the long-term prognostic significance of PAC documented by 7-day Holter recording with regard to the risk of late recurrence of AF after PVI.…”

mentioning

confidence: 99%

Atrial Ectopy Predicts Late Recurrence of Atrial Fibrillation After Pulmonary Vein Isolation

Gang

Nalliah

Lim

et al. 2015

Circ: Arrhythmia and Electrophysiology

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“…Recently, this was also confirmed for patients with congenital heart disease . The predictive value of AES for development of AF recurrences was mainly examined after PVI in patients with PAF, whereas the present study evaluates the value of AES prior to PVI in both PAF and PeAF patients. Gang et al showed in a prospective study in 220 patients with PAF that ≥142 AES/day on the 6 months Holter recording was associated with a higher risk of AF recurrences after PVI (HR 2.84).…”

Section: Discussionmentioning

confidence: 68%

Early markers of atrial fibrillation recurrence after pulmonary vein isolation

Lanters

Teuwen

Hokken

et al. 2020

Journal of Arrhythmia

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Background Postprocedural atrial extrasystole (AES) frequency predicts atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) in patients with paroxysmal AF. However, the predictive value of preprocedural AES frequency is unknown. We investigate whether preprocedural AES frequency is a feasible marker to predict (timing of) AF recurrence after PVI. Methods Patients (N = 684) with paroxysmal or persistent AF undergoing first‐time PVI were evaluated for (a) the frequency of AES/day on Holter recordings without AF prior to PVI, (b) AF episodes during the 90 days blanking period, and (c) AF recurrences afterward. The correlation between AES/day and both development and timing of AF recurrences was tested. Results Preprocedural AES/day was similar in patients with paroxysmal (66 [20‐295] AES/day) and persistent AF (115 [12‐248] AES/day, P = .915). During the blanking period, 302 (44.2%) patients showed AF episodes. AF recurred in 379 (55.4%) patients at 203 (105‐400) days after PVI. AF recurred more frequently in patients with persistent (N = 104 [69.3%]) than in patients with paroxysmal AF (N = 275 [51.5%], P < .001). Frequency of AES prior to PVI was not correlated with development (P = .203) or timing (P = .478) of AF recurrences. AF recurrences occurred both more frequently (P < .001) and earlier (P < .000) in patients with AF during the blanking period. Conclusion AES/day prior to PVI is not correlated with (timing of) AF during the blanking period or AF recurrences, and is therefore not a feasible marker for AF recurrences in patients with PAF. AF during the blanking period is correlated with AF recurrence.

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“…the operation was associated with increased number of PAC. 18 Vincenti et al demonstrated that ectopic beats were more frequent in the hour preceding the onset of AF and, in addition, they observed that AF triggering ectopic beats had shorter coupling interval when compared to the nontriggering ectopic beats. 19 The aforementioned assertion is supported by the study of Yamane et al, where they observed that successful pulmonary vein isolation significantly increased the coupling interval of PACs whereas in patients with unsuccessful operations, the coupling interval prolonged only transiently.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, Yamane et al. noticed that successful pulmonary vein isolation drastically reduced PAC count and that the recurrence of AF after the operation was associated with increased number of PAC . Vincenti et al.…”

Section: Discussionmentioning

confidence: 99%

Supraventricular premature beats and risk of new‐onset atrial fibrillation in coronary artery disease

Nortamo

Kenttä

Ukkola

et al. 2017

Cardiovasc electrophysiol

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Behavior of atrial ectopic beats before and after pulmonary vein isolation in patients with atrial fibrillation: A reduction in the number and arrhythmogenicity of ectopic firings

Cited by 25 publications

References 14 publications

Atrial Ectopy Predicts Late Recurrence of Atrial Fibrillation After Pulmonary Vein Isolation

Atrial Ectopy Predicts Late Recurrence of Atrial Fibrillation After Pulmonary Vein Isolation

Early markers of atrial fibrillation recurrence after pulmonary vein isolation

Supraventricular premature beats and risk of new‐onset atrial fibrillation in coronary artery disease

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