The presence of the openings negatively effects on the strength of the beams where they act as a weak point because of the sudden change in the cross-section of the beam, so it becomes necessary to make strengthening for the beams to resist the effect of the openings and improve the strength of the beams, especially if the beams are subjected to repeated loads because of its effect on the strength at the failure. This paper studies the effect of the openings on the beams subjected to repeated loading and determine the extent of the increase in the strength of the beams when strengthened by the NSM technique. The experimental program included casting and testing fifteen RC beams, six of them considered as a control beams (three with strengthening and three without strengthening), and nine of them having circular transverse openings in different locations and strengthened by the NSM technique. Every type of beams is tested under three different types of loads (monotonic, constant repeated load, and incremental repeated load). All of the beams have the same dimensions and same reinforcement. The results show that all the beams with transverse openings are affected by repeated loads where the ultimate torque decreases and the twist angle increases. The existence of openings has a noted effect on reducing the ultimate torque, whereas the percentage of decrease in the ultimate torsional capacity reached 43.83% at the beam where the opening location is closest to the support (at the quarter of the clear span) and subjected to constant repeated loads, and the ultimate torque is significantly improved when the opening position is moved away from the supports. Also, the existence of strengthening reduced or eliminated the influence of openings on the ultimate torque compared with related non- strengthened beams.