Behavioral and Pharmacological Treatment of Compulsive Sexual Behavior/Problematic Hypersexuality

Leppink, Eric W.; Grant, Jon E.

doi:10.1007/s40429-016-0122-y

Cited by 7 publications

(8 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[150][151][152] For example, molecules already tested for substance use disorders may also be used for BAs. This is the case for opioid antagonists such as naltrexone, which was tested in patients with compulsive sexual behavior 22 or GbD, 153,154 or nalmefene, which was tested in patients with GbD. 155 Moreover, a transversal approach would permit clinicians to not surcharge for multiple therapies and improve the impact of therapies because of co-occurrences.…”

Section: Expected Results and Clinical Implicationsmentioning

confidence: 99%

“…21 Finally, even if international classifications have not yet classified compulsive sexual behavior disorder as an addiction, clinicians have already proposed some treatments recognized as effective in the field of addiction, such as cognitive behavioral therapy and motivational interviewing. 22 Pharmacological treatments, such as naltrexone, which is known to inhibit dopamine release in the ventral part of the striatum and is used as a treatment to regulate craving in alcohol use disorder, have been used with patients with a compulsive sexual behavior disorder and resulted in improvements in their symptoms. [22][23][24] These arguments are thus in favour of considering compulsive sexual behavior disorder as a BA, which could permit the expansion of alternative treatments and research, thereby providing benefit to patients.…”

Section: Background and Rationale Behavioral Addictionsmentioning

confidence: 99%

“…22 Pharmacological treatments, such as naltrexone, which is known to inhibit dopamine release in the ventral part of the striatum and is used as a treatment to regulate craving in alcohol use disorder, have been used with patients with a compulsive sexual behavior disorder and resulted in improvements in their symptoms. [22][23][24] These arguments are thus in favour of considering compulsive sexual behavior disorder as a BA, which could permit the expansion of alternative treatments and research, thereby providing benefit to patients. 25 The concept of FA emerged during the previous century, but human research has primarily emerged in the last decade.…”

Section: Background and Rationale Behavioral Addictionsmentioning

confidence: 99%

See 2 more Smart Citations

A Case–Control Study on Behavioral Addictions and Neurocognition: Description of the BANCO and BANCO2 Protocols

Hurel¹,

Grall‐Bronnec²,

Thiabaud³

et al. 2021

NDT

View full text Add to dashboard Cite

Introduction: Only two behavioral addictions (BAs) are currently recognized in international classifications (gambling disorder: GbD; gaming disorder: GmD), while some of them await further investigation (food addiction: FA; sexual addiction: SA). Neurocognitive functioning is considered a risk factor for BAs. Research is quite abundant for GbD and highlights specific deficits in several cognitive functions. Nevertheless, grey areas still exist. The aim of this research programme is to investigate the neurocognitive profiles of patients presenting with various BAs and to establish parallels between different forms of BA to achieve a common addiction concept. Methods and Analysis: This research program is composed of two studies sharing the same methodology but focusing on different samples: the BANCO study aims to include 30 individuals with a GbD, whereas the BANCO2 study aims to include 30 individuals with a GmD, 30 with a SA, and 30 with a FA. Moreover, for each BA group, 30 healthy controls will be recruited, matched by sex, age and education level. Several cognitive tasks will be completed by participants. Cue reactivity and physiological responses, as well as clinical data regarding addiction characteristics and personality, will also be investigated. A composite score based on the cognitive tasks will be computed using principal component analysis (PCA). Overall cognitive performance and detailed performance on the different cognitive tasks will be compared between individuals with BAs and their matched healthy controls using linear models with random effects. Comparisons will also be made between BA groups to investigate specific alterations associated with each disorder. Discussion: The results of this research programme will impact both research and clinical areas by (i) providing new knowledge for discussions regarding the inclusion of BAs under the spectrum of addictive disorders; (ii) improving understanding of addiction mechanisms in general; (iii) providing clarity in the grey areas in neurocognitive research on BAs and improving the understanding of less studied BAs, (iv) guiding clinicians to propose therapeutic alternatives and complementary programmes.

show abstract

Section: Expected Results and Clinical Implicationsmentioning

confidence: 99%

Section: Background and Rationale Behavioral Addictionsmentioning

confidence: 99%

Section: Background and Rationale Behavioral Addictionsmentioning

confidence: 99%

See 1 more Smart Citation

A Case–Control Study on Behavioral Addictions and Neurocognition: Description of the BANCO and BANCO2 Protocols

Hurel¹,

Grall‐Bronnec²,

Thiabaud³

et al. 2021

NDT

View full text Add to dashboard Cite

show abstract

“…Serotonergic and antiepileptic drugs have been widely used in hypersexuality (15). We have chosen paroxetine for severe depressive symptoms and risperidone -one of the potent second generation antipsychotics, which may decrease sexual arousal and desire.…”

Section: Discussionmentioning

confidence: 99%

Hypersexuality Manifesting As Excessive Masturbation In A Female Patient After Temporal Lobe Epileptic Surgery: A rare case report

Gündüz

Turan

Polat

2019

Archives of Neuropsychiatry

View full text Add to dashboard Cite

Interictal sexual behavior changes are frequently reported in patients with epilepsy, especially those with temporal lobe epilepsy. Changes in sexual function after temporal lobe epileptic surgery can vary within a wide range, ranging from disappearance of paraphilias existing in preoperative period, decreased libido or sexual activity, sexual arousal and orgasmic disorders, sexual activity arising to a normally acceptable level, or hypersexuality. Hypersexuality can be defined as having excessive sexual arousal and drive in abnormal frequency and intensity. Many hypotheses have been developed to explain etiology in hypersexuality in the literature. But there is no consensus on treatment. Here we aimed to present diagnosis and treatment process of hypersexuality manifesting as excessive masturbation in 38 years old, single female patient who underwent selective hippocampectomy (temporal lobe resection) 11 years ago.

show abstract

“…9 Previous reports also suggested that topiramate and naltrexone, medications used for the treatment of some types of substance addiction, may have a therapeutic effect in sexually addicted patients. 10 Of prognostic relevance, studies with substance addicts have described that sexual addiction is associated with increased relapse rates. One possible explanation is that both addictions are often complementary, many addicts reporting the simultaneous use of substances and sex to experience an enhanced effect.…”

Section: Introductionmentioning

confidence: 99%

Sexual addiction in drug addicts: The impact of drug of choice and poly-addiction

António

Diehl

Niel

et al. 2017

Rev. Assoc. Med. Bras.

View full text Add to dashboard Cite

Objective:To compare the risk of comorbid sexual addiction in a sample of individuals with a diagnosis of substance dependence, stratifying the sample by drug of choice as well as by mono versus polysubstance addiction. Method: All data were collected at Santa Casa de São Paulo, Brazil. The study sample comprised all alcohol or drug dependents admitted to the Addiction Treatment Unit between November 2013 and August 2014. A generalized linear model with a binomial distribution was performed to compare the odds of having a Sexual Addiction Screening Test (SAST) score greater than 6 points in the subgroups analyzed. Results: A total of 133 participants were included in our analysis, all reporting cocaine/crack and/or alcohol as drug of choice. Polysubstance addicts had a significant higher risk of a positive screening for sexual addiction compared to monosubstance addicts, age-sex adjusted odds ratios of sexual addiction being respectively 2.72 (95CI 1.1-6.71) and 0.37 (95CI 0.15-0.91). The odds of a SAST score greater than 6 was not statistically different between the cocaine/crack and alcohol groups, respectively 0.38 (95CI 0.14-1.02) and 2.67 (95CI 0.98-7.25). We found a significant relation between stronger drug addiction and greater levels of sexual addiction in the cocaine/crack group (p=0.0012), but not in the alcohol group. Conclusion: Our study reinforces the importance of assessing sexual behavior of drug addicts in clinical practice, especially considering users of multiple substances or with severe dependence.

show abstract

Behavioral and Pharmacological Treatment of Compulsive Sexual Behavior/Problematic Hypersexuality

Cited by 7 publications

References 49 publications

A Case–Control Study on Behavioral Addictions and Neurocognition: Description of the BANCO and BANCO2 Protocols

A Case–Control Study on Behavioral Addictions and Neurocognition: Description of the BANCO and BANCO2 Protocols

Hypersexuality Manifesting As Excessive Masturbation In A Female Patient After Temporal Lobe Epileptic Surgery: A rare case report

Sexual addiction in drug addicts: The impact of drug of choice and poly-addiction

Contact Info

Product

Resources

About