Behavioral Research in Cancer Prevention and Control

Klein, William M. P.; Bloch, Michele; Hesse, Bradford W.; Green, Paige; Nebeling, Linda; O’Connell, Mary Ellen; Riley, William T.; Taplin, Stephen H.; Tesauro, G

doi:10.1016/j.amepre.2013.10.004

Cited by 53 publications

(43 citation statements)

References 95 publications

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“…(10,11) The cancer-screening literature has applied theoretical models of behavior change and demonstrated that patients' poor knowledge, negative attitudes, or perceived barriers to cancer screening may be associated with lower screening rates. (12,13) However, most studies evaluating HCC surveillance correlates have primarily focused on patient sociodemographic and clinical characteristics. (7,14) The effect of theory-based, patient-reported psychosocial factors on HCC surveillance completion has not been quantified.…”

Section: Introductionmentioning

confidence: 99%

Patient‐reported barriers are associated with lower hepatocellular carcinoma surveillance rates in patients with cirrhosis

Farvardin

Patel

Khambaty³

et al. 2016

Hepatology

148

130

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Over 20% of patients with cirrhosis are nonadherent with hepatocellular carcinoma (HCC) surveillance recommendations; however, few studies have evaluated the impact of patient-level factors on surveillance receipt. We characterized the association between HCC surveillance receipt and patient knowledge, attitudes, and perceived barriers in a racially diverse and socioeconomically disadvantaged cohort of patients with cirrhosis. Patients with cirrhosis followed at a large urban hospital were invited to complete a survey about HCC surveillance between August 2014 and December 2015. Multivariable logistic regression was performed to identify factors associated with HCC surveillance receipt during the 12-month period preceding and 6-month period after survey administration. We achieved a response rate of 71.8% (n = 541 of 753). Patients demonstrated high levels of HCC-related knowledge (summary score, 77.7%); however, 48.6% believed that eating a healthy diet precluded the need for HCC surveillance, and 34.0% believed that HCC surveillance was not necessary if they had a normal physical exam and/or lacked clinical symptoms. Patients expressed worry about developing and dying from HCC, but nearly half (49.9%) of patients reported barriers to receiving HCC surveillance, including difficulty with the scheduling process (30.5%), costs of surveillance testing (25.3%), and transportation difficulties (17.3%). HCC surveillance receipt was significantly higher in patients who knew cirrhosis is a risk factor for developing HCC (odds ratio [OR], 3.09; 95% confidence ADDRESS CORRESPONDENCE AND REPRINT REQUESTS TO: Amit G. Singal, M.D., M.S., Division of Digestive and Liver Diseases, UT Southwestern Medical Center, 5959 Harry Hines Boulevard, POB 1, Suite 420, amit.singal@utsouthwestern.edu,. * These authors contributed equally to this work and are co-first authors.Potential conflict of interest: Dr. Singal consults for and is on the speakers' bureau for Bayer. Dr. Yopp is on the speakers' bureau for Bayer and received grants from Novartis and Peregrine.Author names in bold designate shared co-first Although provider recommendation is reported to be a strong predictor for HCC surveillance, (9) patient-level factors may also play an important role in surveillance underuse. In prospective cohort studies, nearly 1 in 5 patients were nonadherent with provider recommendations for HCC surveillance. (10,11) The cancer-screening literature has applied theoretical models of behavior change and demonstrated that patients' poor knowledge, negative attitudes, or perceived barriers to cancer screening may be associated with lower screening rates. (12,13) However, most studies evaluating HCC surveillance correlates have primarily focused on patient sociodemographic and clinical characteristics. (7,14) The effect of theory-based, patient-reported psychosocial factors on HCC surveillance completion has not been quantified. A better understanding of patient knowledge, attitudes, and barriers, particularly among low-income minorities, i...

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Section: Introductionmentioning

confidence: 99%

Patient‐reported barriers are associated with lower hepatocellular carcinoma surveillance rates in patients with cirrhosis

Farvardin

Patel

Khambaty³

et al. 2016

Hepatology

148

130

View full text Add to dashboard Cite

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“…The number of diseases related to lifestyle factors as stress, obesity [1][2][3], excessive consumption of industrialized food containing additives, colorings, trans fats, and other ingredients [4][5][6][7], as well heavy workload [8], sedentary lifestyle, and environmental pollutants has been strongly increased [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

“…Besides, many people rely on herbal medicines for weighting loss since it seems to be an easier way instead of making diet and changing lifestyle and calorie ingestion, that requires efforts [1][2][3]14]. This kind of supplements is very popular and commonly used worldwide and in Brazil [15,16] and also used as adjuvant to nutrition and physical activity, and as such, has less or no side effects when compared to traditional pharmacological treatments [17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

Metals Content in Herbal Supplements

Barrella

Heringer

Cardoso

et al. 2016

Biol Trace Elem Res

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Obesity has become an international epidemic. To evaluate the level of metals in extracts of plants prescribed as weight loss supplements, different brands containing Camellia sinensis (L.) Kuntze, Citrus aurantium L., Cordia ecalyculata Vell, Ilex paraguariensis A. St.-Hil, Cissus quadrangularis L., Senna alexandrina Mill were purchased in local market, hot acid digested, and analyzed while metal content by inductively coupled plasma optical emission spectrometry, ICP-OES. Quality assurance and quality control tests were carried out in order to monitor and control the reliability of the analytical method. For each metal evaluated, a calibration curve was prepared with certified reference material. The recovery test was performed for each batch of samples. Analyses were performed in triplicate. Quantification of aluminum, barium, cadmium, cobalt, chromium, copper, iron, lithium, manganese, molybdenum, nickel, lead, vanadium, and zinc were determined. The metals most frequently detected were manganese (15.3-329,60 mg kg) aluminum (11.76-342.4 mg kg), and iron (11.14-73.01 mg kg) with higher levels in products containing C. sinensis China origin, I. paraguariensis Brazilian origin, C. quadrangularis, and C. aurantium China origin, respectively. To ensure safety consumption, an adequacy of the certification of Brazilian suppliers for herbal weight loss products is indispensable.

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“…In addition, emerging evidence suggests that interactions of health behaviors are related to cancer progression [16]. Recognizing that obesity has economic effects on our state, North Carolina leaders have promoted the Eat Smart, Move More initiative, which aims to increase the number of North Carolinians who are maintaining a healthy weight.…”

Section: North Carolina Counties and Regionsmentioning

confidence: 99%

“…Cancer prevention and control strategies hinge on effective application of knowledge about human behavior [16]. Because smoking prevalence is high in Eastern North Carolina, smoking cessation and prevention are important public health initiatives-not just for cancer but also for many chronic diseases.…”

Section: North Carolina Counties and Regionsmentioning

confidence: 99%