Behavioural differences between artificially selected aggressive and non-aggressive mice: response to apomorphine

Benus, R.F.; Bohus, B.; Koolhaas, Jaap M.; Oortmerssen, G.A. van

doi:10.1016/s0166-4328(05)80072-5

Cited by 82 publications

(41 citation statements)

References 16 publications

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“…For instance, in rodents and pigs [1,9], the DA receptor agonist apomorphine produced a greater enhancement of stereotyped behavior in proactive coping individuals than in reactive coping individuals. Furthermore, it was shown that proactive mice have lower 5-HT neurotransmission [27] and (possibly), consequently, a more sensitive (postsynaptic) 5-HT receptor system as compared to reactive mice [44].…”

Section: Da and 5-ht Turnover Coping And Feather Peckingmentioning

confidence: 99%

Adrenocortical reactivity and central serotonin and dopamine turnover in young chicks from a high and low feather-pecking line of laying hens

Hierden

Korte

Ruesink

et al. 2002

Physiology & Behavior

114

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Adrenocortical reactivity and central serotonin and dopamine turnover in young chicks from a high and low feather-pecking line of laying hens van Hierden, YM; Korte, SM; Ruesink, EW; van Reenen, CG; Engel, B; Korte-Bouws, GAH; Koolhaas, JM; Blokhuis, HJ Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum. AbstractFeather pecking in domestic fowl is a behavioral abnormality that consists of mild or injurious pecking at feathers of conspecifics. Previously, it was shown that chicks from a high feather-pecking (HFP) and low feather-pecking (LFP) line of laying hens already differ in their propensity to feather peck at 14 and 28 days of age. As a first step in investigating a possible relationship between the development of feather pecking and physiological and neurobiological characteristics of laying hens, two subsequent experiments were carried out. Firstly, we investigated the development of adrenocortical (re)activity in HFP and LFP chicks during the first 8 weeks of life. Secondly, we studied dopamine (DA) and serotonin (5-HT) turnover in the brain of 28-day-old HFP and LFP chicks. In both experiments, chicks were exposed to manual restraint (placing the chicks on its side for 5 min). Plasma corticosterone levels were lower (baseline on Days 3 and 56; restraintinduced on Days 3, 14 and 28) in HFP chicks. Both brain DA and 5-HT turnover were lower in the HFP chicks, as well. Possible consequences for the observed differences in (stress) physiology and neurobiology between the two lines in relation to the feather pecking are discussed. D

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Section: Da and 5-ht Turnover Coping And Feather Peckingmentioning

confidence: 99%

Adrenocortical reactivity and central serotonin and dopamine turnover in young chicks from a high and low feather-pecking line of laying hens

Hierden

Korte

Ruesink

et al. 2002

Physiology & Behavior

114

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“…Individuals at one end of the distribution are rather bold in approaching novel stimuli, and have a high tendency to develop routine-like behaviour patterns that are relatively independent of actual information. Individuals at the other end, in contrast, show more caution in making decisions, monitor even a relatively familiar environment extensively, and are therefore able to Xexibly adjust their behaviour to subtle environmental changes (see Benus et al 1991;Koolhaas et al 2001 for review).…”

Section: Introductionmentioning

confidence: 99%

Spatial learning in pigs: effects of environmental enrichment and individual characteristics on behaviour and performance

et al. 2008

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This study investigated the eVects of both environmental enrichment and individual behavioural characteristics on spatial cognitive capabilities of pigs, using a novel latent spatial learning paradigm based on Tolman's detour experiments (1948). Pigs were housed either in 'barren' pens or in pens enriched with straw bedding from birth. Pigs were restrained in a Backtest at 10 and 17 days postpartum. Based on their escape behaviour in this test, which has been shown to reXect their behavioural style, six 'high-resisting'(HR) and six 'low-resisting' (LR) pigs were selected from each housing environment (n = 24 in total). At 12 weeks of age, pairs of pen mates (LR and HR) were exposed to a maze three times (exploration trials). Pigs were then placed individually in the maze, and social reinstatement proved to be a strong incentive to Wnd the exit leading to the home pen. We subsequently blocked the direct route to the exit, forcing animals to Wnd a detour (memory test 1, MT1). This test was repeated once to investigate the relative improvement, i.e. detour learning (memory test 2, MT2). Housing condition and Backtest response strongly aVected exploration patterns. In spite of this, no eVects on performance during the subsequent memory tests were found. Performance was substantially improved in MT2, indicating that once a goal is apparent, pigs are able to solve a complex spatial memory task easily. In conclusion, social reinstatement provided a good incentive to complete a spatial task, and the substantial improvement in performance between MT1 and MT2 stresses the need for task complexity when testing spatial memory in pigs. Housing conditions or individual behavioural style did not aVect spatial memory during MT1 or MT2. However, housing environment and behavioural style strongly aVected explorative behaviour of pigs in an unfamiliar maze during both exploration trials and memory tests. This implicates that apparent eVects of environmental enrichment on spatial learning and memory in pigs might reXect diVerences in explorative patterns rather than in cognitive processes.

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“…These mouse strains were produced by artificial selection for attack latency about 25 years ago [26] and were amply characterized since than [27][28][29][30][31][32]. In brief, SALs show dramatically lower attack latencies, and higher attack counts than LALs.…”

Section: Introductionmentioning

confidence: 99%

Patterns of violent aggression-induced brain c-fos expression in male mice selected for aggressiveness

Haller

Tóth

Halász

et al. 2006

Physiology & Behavior

141

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Behavioural differences between artificially selected aggressive and non-aggressive mice: response to apomorphine

Cited by 82 publications

References 16 publications

Adrenocortical reactivity and central serotonin and dopamine turnover in young chicks from a high and low feather-pecking line of laying hens

Adrenocortical reactivity and central serotonin and dopamine turnover in young chicks from a high and low feather-pecking line of laying hens

Spatial learning in pigs: effects of environmental enrichment and individual characteristics on behaviour and performance

Patterns of violent aggression-induced brain c-fos expression in male mice selected for aggressiveness

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