Behçet’s syndrome: unusual multisystem involvement and immune complexes

Hyman, Nigel; Sagar, H. J.

doi:10.1136/pgmj.56.653.182

Cited by 7 publications

(2 citation statements)

References 16 publications

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“…The beneficial effect of steroid therapy has not been convincing in most series2,7,30. It may control the disease initially, but recurrences are common.…”

Section: Discussionmentioning

confidence: 99%

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Intestinal Perforations in Behçet’s Disease

Chou

Chen

Jan

et al. 2007

Journal of Gastrointestinal Surgery

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Behçet's disease accompanied by intestinal involvement is called intestinal Behçet's disease. The intestinal ulcers of Behçet's disease are usually multiple and scattered and tend to perforate easily, so that many patients require emergency operation. The aim of this study is to determine the extent of surgical resection necessary to prevent reperforation and to point out the findings of concurrent oral and genital ulcers and multiple intestinal perforations in all patients of our series. During a 25-year study period, information of 125 Behçet's disease cases was gathered. Among the 82 patients who were diagnosed with intestinal Behçet's disease, 22 cases had intestinal perforations needing emergency laparotomy. We investigated and analyzed these cases according to the patients' demographic characteristics, clinical presentations, laboratory data, and surgical outcome. There were 14 men and 8 women ranging from 22 to 65 years of age. Nine cases were diagnosed preoperatively, and the diagnoses were confirmed in all 22 cases during the surgical intervention. Surgical resection was performed in every patient, with right hemicolectomy and ileocecal resection in 11 cases, partial ileum resection in 8 cases with two reperforations, and ileocecal resection in 3 cases with one reperforation.

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“…The beneficial effect of steroid therapy has not been convincing in most series2,7,30. It may control the disease initially, but recurrences are common.…”

Section: Discussionmentioning

confidence: 99%

“…A review of the literature reveals that involvement of the gastrointestinal tract is not infrequent. Most cases reported in the literature are in the eastern Mediterranean countries and Japan5–7. We report here a series of 22 cases of intestinal Behçet’s disease with multiple perforations, treated by emergency surgical resections.…”

Section: Introductionmentioning

confidence: 99%