Beliefs of Immunosuppressive Medication Among Chinese Renal Transplant Recipients, as Assessed in a Cross-Sectional Study With the Basel Assessment of Adherence to Immunosuppressive Medications Scale

Association Between Regulatory Emotional Self-Efficacy and Immunosuppressive Medication Adherence in Renal Transplant Recipients:Does Medication Belief Act as a Mediator?

“…Medication belief is a modifiable cognitive factor that predicts medication adherence more than clinical and sociodemographic factors (Horne, 2006;Parekh et al, 2011). Many studies have indicated that medication belief affects medication adherence, and this conclusion also applies to patients after renal transplantation, which was confirmed in our previous study (Xia et al, 2019). The Necessity-Concerns Framework (NCF) assumes that the individual's medication adherence behavior is jointly affected by medication beliefs (including the necessity of prescribed medication and medication-related concerns) and other factors (demographic sociology, disease, psychology, society, etc.).…”

“…This result was different from others. In many studies, including our group's previous research, the most common non-adherence behavior was taking a dose more than 2 h before or after the prescribed time (Cossart et al, 2019;Xia et al, 2019). In our study, among the 38 patients who had changed the prescribed amount of immunosuppressive medication without doctor's permission, 32(84.21%) were more than half a year after surgery.…”

“…Patients who were married and had better immunosuppressive medication beliefs showed better immunosuppressive medication adherence, consistent with our previous findings. However, the two studies used different assessment tools for immunosuppressive medication beliefs: the former used a self-developed immunosuppressive medication beliefs questionnaire, while the present study used the Chinese version of the BMQ (Xia et al, 2019). Compared to unmarried recipients, married recipients were more likely to adhere to medication after transplantation.…”

“…Numerous studies have indicated that the incidence of immunosuppressive medication non-adherence in renal transplant patients ranges from 20 to 70% (Weng et al, 2013;Liu et al, 2015;Reese et al, 2017;Paterson et al, 2018;Xia et al, 2019). This may be due to the difference in immunosuppressive medication adherence measurement tools and assessment criteria in renal transplant patients.…”

“…It is a large challenge for them to strictly adhere to the schedule and dosage of immunosuppressive medication. Among solid organ transplant patients, renal transplant patients had the highest immunosuppressive medication non-adherence (Mellon et al, 2017), ranging from 20 to 70% (Weng et al, 2013;Liu et al, 2015;Reese et al, 2017;Paterson et al, 2018;Xia et al, 2019). Many studies have reported nonadherence (i.e., not taking medication as prescribed) as a primary reason for renal transplant failure (Weng et al, 2013;Gaynor et al, 2014;Prihodova et al, 2014).…”