Bell's palsy and its treatment

Aminoff, M. J.

doi:10.1136/pgmj.49.567.46

Cited by 8 publications

(7 citation statements)

References 50 publications

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“…The narrowest portion is found at the entrance. 10,37,38,[42][43][44][45][46] There is a less than 50 per cent chance of a spontaneous, complete recovery in those aged over 60 years. 8,37 Natural course About 70 per cent of patients recover completely without any therapy, 38,39 and 15 per cent more might still have a 'good' recovery.…”

Section: Pathophysiologymentioning

confidence: 99%

“…8,10,25,45,50,[55][56][57][58][59][60][61][62][63] Over the last 15 years, patients in our clinics with moderate and severe palsy (House-Brackmann grades IV, V and VI ) have been treated with corticosteroids and antivirals. Firstly, treatment should start as early as possible.…”

Section: Current Treatmentmentioning

confidence: 99%

“…10,64,65 Our questions are as follows. This issue is important because on average 85 per cent of patients have a 'rather good' recovery without therapy.…”

Section: Treatment Revisitedmentioning

confidence: 99%

“…Although it refers to a supposedly ‘idiopathic’ lesion, many theories have been developed. Bell's palsy has been attributed to cold exposure, chill or rheumatism 10 – 12 . Nowadays, most literature suggests that Bell's palsy is caused by infection with the herpes simplex virus 13 – 20 or varicella zoster virus 21 – 25 .…”

Section: Pathophysiologymentioning

confidence: 99%

“…Patients with an initial severe palsy, the elderly and patients with diabetes have a higher chance of non-recovery or complications 10 , 37 , 38 , 42 – 46 . There is a less than 50 per cent chance of a spontaneous, complete recovery in those aged over 60 years.…”

Section: Natural Coursementioning

confidence: 99%

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Antiviral agents convey added benefit over steroids alone in Bell's palsy; decompression should be considered in patients who are not recovering

Brennan

Martens

2015

J. Laryngol. Otol.

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Section: Pathophysiologymentioning

confidence: 99%

Section: Current Treatmentmentioning

confidence: 99%

“…10,64,65 Our questions are as follows. This issue is important because on average 85 per cent of patients have a 'rather good' recovery without therapy.…”

Section: Treatment Revisitedmentioning

confidence: 99%

Section: Pathophysiologymentioning

confidence: 99%

Section: Natural Coursementioning

confidence: 99%

See 3 more Smart Citations

Antiviral agents convey added benefit over steroids alone in Bell's palsy; decompression should be considered in patients who are not recovering

Brennan

Martens

2015

J. Laryngol. Otol.

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Perhexiline neuropathy: A clinicopathological study

Saïd

1978

Annals of Neurology

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Five patients developed a mild to severe polyneuropathy while under treatment with perhexiline maleate, a drug used in long-term treatment of angina pectoris. Recovery took place within a few months after drug withdrawal. We performed qualitative and quantitative light and electron microscopical studies, including teased fiber preparations, in different patients; 16 to 90% of the fibers showed segmental demyelination, an unusual feature in drug-induced neuropathies, and 3 to 20% were undergoing wallerian degeneration. Severe loss of myelinated axons was noted in all 5 patients. In these patients clinical symptoms occurred only when a great number of fibers had already been lost and most of the surviving fibers showed demyelination.

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The True Nature of Bell's Palsy: Analysis af 1,000 Consecutive Patients

et al. 1978

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In a series of 1502 patients seen in our Facial Paralysis Research Clinic 1048 were diagnosed as having Bell's palsy. Review of clinical, epidemiologic, and laboratory data, plus review of the literature, has led to the conclusion that Bell's palsy is an acute benign cranial polyneuritis probably caused by reactivation of the herpes‐simplex virus, and the dysfunction of the motor cranial nerves (V, VII, X) may represent inflammation and demyelinization rather than ischemic compression. Spinal fluid analysis suggests that the disease is a phenomenon of the central nervous system with secondary peripheral neural manifestations. With our presently available information, treatment of a viral disease with an anti‐inflammatory agent is rational. Prednisone treatment started within the first week of the disease can restore better function to the paralyzed face than is achieved without such therapy, and facial nerve decompression has been unnecessary.

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Bell's palsy and its treatment

Cited by 8 publications

References 50 publications

Antiviral agents convey added benefit over steroids alone in Bell's palsy; decompression should be considered in patients who are not recovering

Antiviral agents convey added benefit over steroids alone in Bell's palsy; decompression should be considered in patients who are not recovering

Perhexiline neuropathy: A clinicopathological study

The True Nature of Bell's Palsy: Analysis af 1,000 Consecutive Patients

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