Bell's palsy during pregnancy: Is it associated with adverse perinatal outcome?

Katz, Ariel; Sergienko, Ruslan; Dior, Uri; Wiznitzer, Arnon; Kaplan, Daniel M.; Sheiner, Eyal

doi:10.1002/lary.21860

Cited by 50 publications

(51 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a study of pregnant women, of 242,000 deliveries, 0.17% of expectant mothers were diagnosed with Bell's palsy. 16 Obesity, chronic hypertension, and severe preeclampsia also increased the risk. Diabetes is also a risk factor, and hypertension may be independently associated with an increased risk of Bell's palsy.…”

Section: Introductionmentioning

confidence: 99%

Clinical Practice Guideline: Bell's Palsy Executive Summary

Baugh

Basura

Ishii

et al. 2013

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Clinical Practice Guideline: Bell's Palsy Executive Summary

Baugh

Basura

Ishii

et al. 2013

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

show abstract

“…The authors concluded that obesity as well as chronic hypertension were independent risk factors for Bell's palsy during pregnancy; however, no significant correlation could be found between facial paralysis and adverse perinatal outcomes. 7 Furthermore, it has even been suggested that Bell's palsy could be a predictor of PE. 4 HELLP syndrome, 8 which was present in case 1, has not been previously reported in association with Bell's palsy occurring during pregnancy.…”

Section: Discussionmentioning

confidence: 99%

Bell's palsy in pregnancy: underlying HELLP syndrome or pre-eclampsia?

Pourrât

Pierre

2013

Obstet Med

View full text Add to dashboard Cite

Bell's palsy is not uncommon during pregnancy. An association with pre-eclampsia (PE) has been reported previously. Furthermore, it has even been suggested that Bell's palsy could be a predictor of PE. We report three cases illustrating various possible aspects of this association, one of them including the features of HELLP (haemolysis, elevated liver enzymes, and low platelets) syndrome.Keywords general medicine, high-risk pregnancy, maternal-fetal medicine, neurology Case reportsThe main features of Bell's palsy and pre-eclampsia (PE) in the three cases are summarized in Tables 1 and 2. Case 1A 29-year-old gravida 1, para 0 woman was admitted to hospital at 39 weeks of gestation with a history of sudden onset of severe epigastric pain. At admission, blood pressure was normal and there was no proteinuria but HELLP (haemolysis, elevated liver enzymes, and low platelets) syndrome was diagnosed: the platelet count had fallen from 133 Â 10 9 /L at 36 weeks to 83 Â 10 9 /L, aspartate aminotransferase was 362 IU/ L, alanine transaminase was 282 IU/L and total bilirubin level was 10 mmol/L (normal range: 1-17). Corticosteroids were given because of low platelet count (betamethasone, 20 mg intravenously/12 hourly) and labour was induced. Four days after delivery, a left facial weakness occurred and progressed to complete isolated Bell's palsy over two days. Methylprednisolone was given intravenously (60 mg/day) for eight days, followed by oral prednisolone (30 mg/day) for four days. There was a moderate improvement over the next few months but permanent residual left facial palsy remained. Serological examination was negative for viruses as well as for antiphospholipid (lupus anticoagulant, anticardiolipin, anti-2 -glycoprotein type I) and antinuclear antibodies. Three years later, a subsequent pregnancy was completed without any complication except for late slight gestational thrombocytopenia. Case 2A 35-year-old gravida 2, para 0 woman was admitted to hospital at 31 weeks of gestation because of right facial weakness. The pregnancy was a twin gestation following intracytoplasmic sperm injection. Facial weakness progressed to complete facial paralysis within two days. Steroid therapy (prednisone 60 mg/day for 5 days) was followed by complete remission of the palsy within eihjt days. At 33 weeks, a diagnosis of PE was made, leading to a decision to perform a caesarean section: the first newborn weighed 1530 g; the second one was growthrestricted (1170 g). Viral serology was negative for varicella zoster (VZV), cytomegalovirus (CMV), parvovirus B19, HIV and hepatitis B. Treponema pallidum particle agglutination assay and Venereal Disease Research Laboratory tests for syphilis were negative, as were antinuclear and antiphospholipid antibodies. Case 3A 27-year-old gravida 1, para 0 woman was admitted to hospital at 34 weeks of gestation because of right facial weakness. A diagnosis of complete idiopathic right facial palsy was made. She was given oral corticosteroid therapy (prednisone 40 mg/day) and acyclovir fo...

show abstract

“…51,54 Most cases of Bell palsy occur in the third trimester (71% to 89.5%), followed by 9.8% to 21.3% in the puerperium, 5.3% in the first trimester, and 2.4% to 2.6% in the second trimester. 49,51,55,56 Controversy exists as to the causative mechanism for Bell palsy in pregnancy, and why it is essentially limited to the third trimester and puerperium. In the general population, speculative causative agents include viral infection, vascular ischemia, autoimmune inflammatory disorders, and hereditary factors.…”

Section: Bell Palsy In Pregnancymentioning

confidence: 98%

“…49 It is acute in onset, unilateral, and is considered to be idiopathic. 50 It occurs in 17 to 25 of 100,000 people annually, equally in males and females, with no predilection for a particular side of the face.…”

Section: Bell Palsy In Pregnancymentioning

confidence: 99%

Headache and Neurological Disease in Pregnancy

Pearce

Hansen²

2012

Clinical Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

A review of the approach in pregnancy to a very commonly encountered neurological disorder (headache), along with less commonly encountered neurological entities that none the less deserve the obstetrician's attention. Definitions of specific disorders and differential diagnoses are reviewed, along with treatment options and pregnancy-associated morbidities. Headache is reviewed first including the common primary headaches migraine and tension-type headache. The disabling neurological disorders-multiple sclerosis, cerebral palsy, and spinal cord injury are grouped due to common morbidities affecting pregnancy. Finally, Bell palsy is also reviewed.

show abstract

Bell's palsy during pregnancy: Is it associated with adverse perinatal outcome?

Abstract: Chronic hypertension and obesity are independent risk factors for Bell's palsy. Bell's palsy during pregnancy is significantly associated with severe preeclampsia. Nevertheless, no significant association exists between Bell's palsy and adverse perinatal outcomes.

Cited by 50 publications

References 15 publications

Clinical Practice Guideline: Bell's Palsy Executive Summary

Clinical Practice Guideline: Bell's Palsy Executive Summary

Bell's palsy in pregnancy: underlying HELLP syndrome or pre-eclampsia?

Headache and Neurological Disease in Pregnancy

Contact Info

Product

Resources

About