Bell's Palsy in an Older Patient with Uncontrolled Hypertension Due to Medication Nonadherence

Ellis, Samuel L.; Carter, Barry L.; Leehey, Maureen A.; Conry, Colleen

doi:10.1345/aph.19129

Cited by 13 publications

(18 citation statements)

References 22 publications

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“…We did not find any independent role for hypertension to cause Bell’s palsy among patients younger than 40 years, but hypertension had an association – although not a very strong one – with Bell’s palsy among older patients. Contrary to diabetes there is less evidence in the literature for hypertension to cause or predispose to Bell’s palsy in the general population [5,6,7,12,13,14,15,28,29,30]. There has been more attention on hypertension in Bell’s palsy among children and pregnant women [31,32,33,34,35,36,37].…”

Section: Discussionmentioning

confidence: 99%

Independent Role of Hypertension in Bell’s Palsy: A Case-Control Study

2008

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Background/Aim: In this case-control study, our aim was to check for a possible independent role of hypertension in increasing the risk of developing Bell’s palsy. Methods: All patients diagnosed as having Bell’s palsy referred to a neurology clinic were enrolled as cases. Controls were selected among other patients referred to the same clinic. Data were analyzed using the Stata 8 statistical software package. To detect the independent effect of exposure variables, a multiple logistic regression test was used. Results: Bivariate analysis showed an increased risk of Bell’s palsy for patients with diabetes or hypertension. Logistic regression results stratified for patients younger than 40 years of age and others showed that diabetes was the independent predictor of Bell’s palsy in both age groups. Logistic regression results showed that hypertension could not independently predict the occurrence of Bell’s palsy among patients younger than 40 years but for older ones it could. Conclusion: Hypertension may increase the risk of Bell’s palsy among those aged above 40 years. Researchers should be very cautious when declaring an independent role of hypertension as a cause of Bell’s palsy.

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Section: Discussionmentioning

confidence: 99%

Independent Role of Hypertension in Bell’s Palsy: A Case-Control Study

2008

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“…The patient had a number of risk factors for Bell's palsy, including hypertension, diabetes, peripheral neuropathy, and a history of herpes labialis. Although longstanding uncontrolled hypertension has been associated with facial paralysis, 30 our patient' s blood pressure was well controlled with lisinopril. The patient's hemoglobin A 1c had been 7.1-7.2% (upper limit of normal), and his fasting blood glucose level was within normal limits throughout both episodes of facial paralysis.…”

Section: Discussionmentioning

confidence: 55%

Bell's Palsy Associated with Linezolid Therapy: Case Report and Review of Neuropathic Adverse Events

Thai

Bruno-Murtha

2006

Pharmacotherapy

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Bell's palsy is one of the most common neurologic disorders affecting the seventh cranial nerve. Several disease states have been associated with facial paralysis. Drugs, however, have been rarely implicated as an etiology. We describe a 49-year-old man who developed peripheral facial paralysis after 3 weeks of linezolid therapy, along with recurrence of symptoms on rechallenge. He had insulin-dependent diabetes mellitus and a longstanding history of bilateral diabetes-related foot problems. After hospitalization, debridement, and vancomycin therapy for methicillin-resistant Staphylococcus aureus osteomyelitis, the patient was discharged to home with oral linezolid therapy. On day 23 of linezolid therapy, he developed signs and symptoms that were consistent with Bell's palsy. Linezolid was discontinued; the Bell's palsy gradually improved, with complete resolution occurring at month 3. On rechallenge with linezolid for recurrent osteomyelitis, the patient developed a second episode of Bell's palsy within a similar time frame as in the first episode. Assessment of causality using the Naranjo adverse drug reaction probability scale revealed a probable relationship between this adverse drug event and linezolid therapy. Clinicians should be aware that Bell's palsy may be another neuropathic adverse effect associated with linezolid.

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“…One case of acute onset of Bell's palsy in 62-year-old female patient was described by Ellis et al, when patient developed severe hypertension with subsequent unilateral facial weakness due to nonadherence with her antihypertensive therapy for 1 week. 18 Our patient presented with hypertension which has been resolved with pain and fever management and could be considered as the least convincing factor contributing to the evolution of her facial paralysis. People who take metoclopramide can develop Bell's palsy as well; however, for those who take it over 5 years the probability of developing facial paralysis declines to 0%.…”

Section: Discussionmentioning

confidence: 78%

New onset of Bell’s palsy in a patient with West Nile Encephalitis

Vaysman

Melkonyan

Liu

2020

Clinical Case Reports

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West Nile virus (WNV) is the leading cause of mosquito-borne disease in the United States and is most commonly spread through an infected mosquito bite even though other modes of transmission such as breastfeeding, transplacental transmission, organ transplantation, blood transfusion, and laboratory acquisition exist. 1 The virus is a member of the Flavivirus genus, making it closely related to the viruses that cause yellow fever, dengue fever, and St Louis encephalitis. 2 The virus was first discovered in Uganda in 1937 and first reported in North America in 1999. 3 Since then, thousands of cases are reported each year with major outbreaks in August and September. 4 To diagnose WNV as the underlying etiology of encephalitis, it is informative to obtain cerebrospinal fluid (CSF) for detection of WNV IgM antibody in addition to the serum antibodies. 5 West Nile virus is the most common cause of viral encephalitis in the United States and is considered a significant contributing cause for numerous cases of neurological dysfunction in the nearest future. 6 According to the US Center for Disease Control and Prevention, approximately 80% of infected people are asymptomatic or have mild symptoms. 7 All ages are affected with highest incidence

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Bell's Palsy in an Older Patient with Uncontrolled Hypertension Due to Medication Nonadherence

Cited by 13 publications

References 22 publications

Independent Role of Hypertension in Bell’s Palsy: A Case-Control Study

Independent Role of Hypertension in Bell’s Palsy: A Case-Control Study

Bell's Palsy Associated with Linezolid Therapy: Case Report and Review of Neuropathic Adverse Events

New onset of Bell’s palsy in a patient with West Nile Encephalitis

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