Bench to Bedside to Bystanders – Moving Antidotes and Management Guidelines Out of the Hospital and Into the Field

Overlapping Science in Radiation and Sulfur Mustard Exposures of Skin and Lung: Consideration of Models, Mechanisms, Organ Systems, and Medical Countermeasures: Overlapping science in radiation and sulfur mustard injuries to lung and skin

“…Toxidrome is defined as the syndromic effect of a toxin, and a threat agnostic approach is to treat the injury, not the threat. 133 Given that scenario, the current research focus is on oxidative stress and how it impacts mammals (largely pigs), as assessed by lung inflammatory cell accumulation, and increased TNF-α, as well as other pro-inflammatory cytokines, lung matrix metalloproteinases, and DNA damage. Several animal species have been studied in SM research: large animals include dogs, sheep, NHPs, and pigs.…”