Beneficial effect of stopping smoking on future cardiac events in male smokers with previous myocardial infarction.

Impact of Smoking Status on Long-Term Mortality in Patients With Acute Myocardial Infarction

“…[5][6][7][8][9][10][11] A recent meta-analysis showed that quitting smoking is associated with reduced risk of total mortality and the pooled crude relative risk was 0.64 (95%CI: 0.58-0.71). 12 In Japan, it has been reported that smoking cessation is associated with reduced second cardiac events (ie, cardiac death and nonfatal MI) in 90 male patients with a history of MI, 27 but that study had the limitations of small sample size, male subjects only and a combined endpoint. Therefore, we examined the impact of smoking cessation on long-term mortality in Japanese AMI patients using a large hospital-based cohort of patients and found that quitters had lower long-term all-cause mortality rates than persistent smokers and a 61% reduction in longterm mortality after AMI.…”

Mortality Risk Reduction Associated With Smoking Cessation in Patients With Coronary Heart Disease

“…Twenty studies 7,8,19,36-52 met all inclusion criteria and had sufficient data available (see appendix 4, authors' Web site). Agreement between the 2 reviewers for study eligibility was very high (weighted = 0.9).…”

“…Eleven 7,8,41,[43][44][45][46][47][48][49][50] of the 20 studies attempted to verify smoking status during the follow-up time period (ie, whether or not the authors contacted patients during the follow-up period to check their smoking status. Mostly this was by self-report); only 2 attempted to assess smoking status biochemically.…”

Changes in Coronary Heart Disease Risk Among Japanese

“…The benefit of smoking cessation also was confirmed for patients with a history of myocardial infarction for the prevention of subsequent cardiac events. 24 In Japan, the prevalence of current smoking has declined from 82% in 1965% to 46% in 2005 for men Ն20 years of age, whereas that for women declined slightly from 16% in 1965% to 12% in 2005. 1,25 However, for women 20 to 29 years old, the prevalence of smoking increased from 7% in 1965 to 21% in 2005.…”