Beneficial effects of Waon therapy on patients with chronic heart failure: Results of a prospective multicenter study

Miyata, Masaaki; Kaburagi, Takashi; Kubozono, Takuro; Ikeda, Yoshiyuki; Shinsato, Takuro; Izumi, Toru; Matsuzaki, Masunori; Yamaguchi, Tetsu; Kasanuki, Hiroshi; Daida, Hiroyuki; Nagayama, Masatoshi; Nishigami, Kazuhiro; Hirata, Kumiko; Kihara, Koichi; Tei, Chuwa

doi:10.1016/j.jjcc.2008.07.009

Cited by 72 publications

(96 citation statements)

References 16 publications

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“…We have already demonstrated significant efficacy of 10-15 sessions of Waon therapy for patients with milder HF. 8,14-17, 21 However, in patients with more advanced HF, such as those enrolled in the present study, more sessions (eg, 20-40 times) of Waon therapy are likely needed to achieve apparent clinical benefits such as left ventricular reverse remodeling. Evidence supporting longterm Waon therapy in patients with advanced HF is be a future concern.…”

Section: Study Limitationsmentioning

confidence: 95%

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Waon Therapy for Managing Chronic Heart Failure　– Results From a Multicenter Prospective Randomized WAON-CHF Study –

Tei

Imamura

Kinugawa

et al. 2016

Circ J

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Background: Waon therapy improves heart failure (HF) symptoms, but further evidence in patients with advanced HF remains uncertain. Methods and Results:In 19 institutes, we prospectively enrolled hospitalized patients with advanced HF, who had plasma levels of B-type natriuretic peptide (BNP) >500 pg/ml on admission and BNP >300 pg/ml regardless of more than 1 week of medical therapy. Enrolled patients were randomized into Waon therapy or control groups. Waon therapy was performed once daily for 10 days with a far infrared-ray dry sauna maintained at 60°C for 15 min, followed by bed rest for 30 min covered with a blanket. The primary endpoint was the ratio of BNP before and after treatment. In total, 76 Waon therapy and 73 control patients (mean age 66 years, men 61%, mean plasma BNP 777 pg/ml) were studied. The groups differed only in body mass index and the frequency of diabetes. The plasma BNP, NYHA classification, 6-min walk distance (6MWD), and cardiothoracic ratio significantly improved only in the Waon therapy group. Improvements in NYHA classification, 6MWD, and cardiothoracic ratio were significant in the Waon therapy group, although the change in plasma BNP did not reach statistical significance. No serious adverse events were observed in either group. Conclusions:Waon therapy, a holistic soothing warmth therapy, showed clinical advantages in safety and efficacy among patients with advanced HF. (Circ J 2016; 80: 827 -834)

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Section: Study Limitationsmentioning

confidence: 95%

“…21 Patients remained seated for 15 min, and then rested supine while covered with a warm blanket for an additional 30 min. All participants were weighed before and after the Waon therapy, and oral hydration with cold water was provided to compensate for the weight loss from perspiration.…”

Section: Waon Therapymentioning

confidence: 99%

Waon Therapy for Managing Chronic Heart Failure　– Results From a Multicenter Prospective Randomized WAON-CHF Study –

Tei

Imamura

Kinugawa

et al. 2016

Circ J

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“…5 In a prospective multicenter study, we have confirmed that Waon therapy is safe, improves clinical symptoms and cardiac function, and decreases cardiac size in CHF patients. 6 Recently, we assessed the impact of Waon therapy on the prognosis of 129 patients with CHF: 64 underwent Waon therapy, 65 did not, and the patients were followed for 5 years. The patients in the Waon group continued the therapy at least twice weekly after discharge.…”

Section: Effect Of Waon Therapy On Chfmentioning

confidence: 99%

Waon Therapy for Cardiovascular Disease: - Innovative Therapy for the 21st Century -

Miyata

Tei

2010

Circ J

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“…19) And they demonstrated that Waon therapy improved clinical symptoms and cardiac function evaluated by 2DE and BNP concentrations, and decreased cardiac size on chest radiography and 2DE after once a day, 2 weeks of Waon therapy in patients with CHF using the movable and sitting-position sauna system. 19) …”

Section: Effect Of Waon Therapy On Heart Failurementioning

confidence: 99%

Preliminary Clinical Experience with Waon Therapy in Korea: Safety and Effect

Sohn

Cho

Kim

et al. 2010

J Cardiovasc Ultrasound

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P Pr re el li im mi in na ar ry y C Cl li in ni ic ca al l E Ex xp pe er ri ie en nc ce e w wi it th h W Wa ao on n T Th he er ra ap py y i in n K Ko or re ea a: : S Sa af fe et ty y a an nd d E Ef ff fe ec ct t Waon therapy has beneficial effects on chronic heart failure (CHF), peripheral arterial disease, and other various diseases. This was to assess the safety and effect of Waon therapy by echocardiography for the first time in Korea. M Me et th ho od ds s: : Ten patients with CHF were enrolled. The patients with a light gown were placed in a sitting-position in an evenly maintained 60˚C dry sauna system for 15 minutes, and then after leaving the sauna, they underwent bed rest with a blanket to keep them warm for an additional 30 minutes. Waon therapy was performed once a day, 5 days a week. R Re es su ul lt ts s: : Four of the 5 patients who had been treated for more than 2 weeks as protocol noted improvement of heart failure (HF) symptoms and decrease in left ventricular (LV) volume. There were trends in improvement of LV ejection fraction and parameters of diastolic function after the therapy although statistical significance was lack. No one complained of worsening of HF symptoms. In each session, body weight (61.8±10.2 kg vs. 61.6±10.3 kg, p=0.008) and blood pressure (systolic, 119±28 vs. 111±27 mmHg, p=0.005; diastolic, 69±12 mmHg vs. 63±10 mmHg, p=0.005) were significantly decreased, oral temperature (35.9±0.4˚C vs. 37.0±0.9˚C, p=0.017) was increased by 1.0˚C at the end of sauna bathing, but the heart rate (71±10/min vs. 72±8/min, p=0.8) was not changed. C Co on nc cl lu us si io on n: : We have experienced Waon therapy which was safe and well tolerated and some beneficial effects for patients with CHF. Large scale randomized study is needed to apply Waon therapy as a promising therapy in Korean HF patients.

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Beneficial effects of Waon therapy on patients with chronic heart failure: Results of a prospective multicenter study

Abstract: Waon therapy is safe, improves clinical symptoms and cardiac function, and decreases cardiac size in CHF patients. Waon therapy is an innovative and promising therapy for patients with CHF.

Cited by 72 publications

References 16 publications

Waon Therapy for Managing Chronic Heart Failure　– Results From a Multicenter Prospective Randomized WAON-CHF Study –

Waon Therapy for Managing Chronic Heart Failure　– Results From a Multicenter Prospective Randomized WAON-CHF Study –

Waon Therapy for Cardiovascular Disease: - Innovative Therapy for the 21st Century -

Preliminary Clinical Experience with Waon Therapy in Korea: Safety and Effect

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Beneficial effects of Waon therapy on patients with chronic heart failure: Results of a prospective multicenter study

Abstract: Waon therapy is safe, improves clinical symptoms and cardiac function, and decreases cardiac size in CHF patients. Waon therapy is an innovative and promising therapy for patients with CHF.

Cited by 72 publications

References 16 publications

Waon Therapy for Managing Chronic Heart Failure – Results From a Multicenter Prospective Randomized WAON-CHF Study –

Waon Therapy for Managing Chronic Heart Failure – Results From a Multicenter Prospective Randomized WAON-CHF Study –

Waon Therapy for Cardiovascular Disease: - Innovative Therapy for the 21st Century -

Preliminary Clinical Experience with Waon Therapy in Korea: Safety and Effect

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Product

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Waon Therapy for Managing Chronic Heart Failure　– Results From a Multicenter Prospective Randomized WAON-CHF Study –

Waon Therapy for Managing Chronic Heart Failure　– Results From a Multicenter Prospective Randomized WAON-CHF Study –