Beneficial Impacts of Choline in Animal and Human With Special Reference to Its Role Against Fatty Liver Syndrome

Saeed, Muhammad; Alagawany, Mahmoud; Arain, Muhammad Asif; El‐Hack, Mohamed E. Abd; Dhama, Kuldeep

doi:10.18006/2017.5(5).589.598

Cited by 10 publications

(11 citation statements)

References 45 publications

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“…An alternative possibility for hepatic hypertrophy is if amino acids are unavailable for protein synthesis, this may suggest they could also be unavailable for other typical functions in the body, such as for example the lipotropic ability of methionine. Methionine works with choline as a methyl donor to export fats from the liver ( Kalbande et al, 2009 ; Saeed et al, 2017 ). Although liver fat was not analyzed in the present study.…”

Section: Discussionmentioning

confidence: 99%

Complete replacement of soybean meal with black soldier fly larvae meal in feeding program for broiler chickens from placement through to 49 days of age reduced growth performance and altered organs morphology

Facey

Kithama²,

Mohammadigheisar³

et al. 2023

Poultry Science

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Section: Discussionmentioning

confidence: 99%

Complete replacement of soybean meal with black soldier fly larvae meal in feeding program for broiler chickens from placement through to 49 days of age reduced growth performance and altered organs morphology

Facey

Kithama²,

Mohammadigheisar³

et al. 2023

Poultry Science

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“…Previous interventions showed that a diet deficient in choline causes serious health problems in humans and animals [ 48 ]. Choline can be used in the treatment of fatty liver syndrome [ 49 ]. Besides having a dietary role, choline supplementation could improve meat quality.…”

Section: Discussionmentioning

confidence: 99%

1H-NMR-Based Metabolomics: An Integrated Approach for the Detection of the Adulteration in Chicken, Chevon, Beef and Donkey Meat

et al. 2021

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Meat is a rich source of energy that provides high-value animal protein, fats, vitamins, minerals and trace amounts of carbohydrates. Globally, different types of meats are consumed to fulfill nutritional requirements. However, the increasing burden on the livestock industry has triggered the mixing of high-price meat species with low-quality/-price meat. This work aimed to differentiate different meat samples on the basis of metabolites. The metabolic difference between various meat samples was investigated through Nuclear Magnetic Resonance spectroscopy coupled with multivariate data analysis approaches like principal component analysis (PCA) and orthogonal partial least square-discriminant analysis (OPLS-DA). In total, 37 metabolites were identified in the gluteal muscle tissues of cow, goat, donkey and chicken using 1H-NMR spectroscopy. PCA was found unable to completely differentiate between meat types, whereas OPLS-DA showed an apparent separation and successfully differentiated samples from all four types of meat. Lactate, creatine, choline, acetate, leucine, isoleucine, valine, formate, carnitine, glutamate, 3-hydroxybutyrate and α-mannose were found as the major discriminating metabolites between white (chicken) and red meat (chevon, beef and donkey). However, inosine, lactate, uracil, carnosine, format, pyruvate, carnitine, creatine and acetate were found responsible for differentiating chevon, beef and donkey meat. The relative quantification of differentiating metabolites was performed using one-way ANOVA and Tukey test. Our results showed that NMR-based metabolomics is a powerful tool for the identification of novel signatures (potential biomarkers) to characterize meats from different sources and could potentially be used for quality control purposes in order to differentiate different meat types.

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“…In day-old chicks, choline is classified as an essential micronutrient because it provides the body with a labile methyl group so that creatine and methionine can be formed. It is essential for bird growth and to prevent perosis [ 8 ]. However, there is no agreement on the appropriate dose.…”

Section: Introductionmentioning

confidence: 99%

Performance, Egg Quality, and Yolk Antioxidant Capacity of the Laying Quail in Response to Dietary Choline Levels

Olgun

Gül

Kilinç

et al. 2022

Animals

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The current study determined the ideal dose of choline in the diet of laying quails based on egg development, egg quality, and antioxidant capacity. A total of 120 female quails (244.7 ± 10.38 g) were randomly assigned to 6 experimental groups with 5 replicates of 4 quails each. In the 10-week trial, treatment diets were formed by adding 6 choline chloride−60% concentrations providing 1500 (control), 2000, 2500, 3000, 3500, and 4000 mg/kg of choline. The feed intake of quails was quadratically affected (p < 0.05) by the choline level of the diet, in other developmental parameters, and by egg quality among these treatments. The feed intake was reduced to 2500 and 3000 mg/kg levels of choline in the diet compared to the control group. Free radical scavenging capacity (DPPH) of the yolk increased linearly (p < 0.001) with dietary choline levels. In contrast, the thiobarbituric acid reactive substances (TBARS) value decreased as dietary choline levels increased, except for 4000 mg/kg levels. Based on the findings of the current study, 1500 mg/kg of dietary choline is adequate to maintain performance parameters and egg quality in laying quails. However, to increase egg antioxidant capacity, in terms of the DPPH value, the dietary choline dose needs to be increased to 3500 mg/kg.

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Beneficial Impacts of Choline in Animal and Human With Special Reference to Its Role Against Fatty Liver Syndrome

Cited by 10 publications

References 45 publications

Complete replacement of soybean meal with black soldier fly larvae meal in feeding program for broiler chickens from placement through to 49 days of age reduced growth performance and altered organs morphology

Complete replacement of soybean meal with black soldier fly larvae meal in feeding program for broiler chickens from placement through to 49 days of age reduced growth performance and altered organs morphology

1H-NMR-Based Metabolomics: An Integrated Approach for the Detection of the Adulteration in Chicken, Chevon, Beef and Donkey Meat

Performance, Egg Quality, and Yolk Antioxidant Capacity of the Laying Quail in Response to Dietary Choline Levels

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