In order to maintain control over tax collection, the State or Government of each country employs different tax regimes so that, according to their conformation, taxpayers comply with the guidelines that allow them to meet their tax commitments, and in turn obtain benefits that favor the formalization and sustainability of their business and contribute to the economic growth of the region. Thus, the objective of this research was to analyze the dynamics and operation of the Simple Tax Regime (RST) as a tool for strengthening microenterprises in Colombia. To this end, the research was developed in three phases: (1) an approach was made to the theoretical definition of the RST in microenterprises in Colombia, based on the consultation of the equation "régimen simple de tributación" OR "simple taxation regime" OR "simple tax regime" OR "simple taxation system", in the WoSTM (0 results), Scopus (2), ScienceDirect® (7), EBSCOhost (95), Springer (31) and ProQuest (530) databases, with the purpose of establishing a reference for Latin America and Colombia on the functioning of this regime. (2) This information was complemented with an expert panel of 20 accountants, who were consulted on the advantages and disadvantages of this system, as well as recommendations for its implementation. (3) Finally, a case study was conducted at Sociedad Ingenieros de la Costa DA SAS (SIC-DA SAS), through which we sought to compare with real figures the application of both regimes and thus identify the main advantages and disadvantages of its implementation, the simplification of processes and lay the groundwork for making decisions that do not affect the company's finances. The results show that the implementation of simple tax systems encourages economic growth and tends to avoid corruption through business formalization.This situation is evidenced in the benefits granted by the RST that taxes total income at low rates, unlike the RO, as could be corroborated in the case applied to SIC-DA SAS whose implementation would improve its cash flow, allowing reinvestment in its growth.