Benefit and safety of 28-day transdermal estrogen regiment during vaginal hysterectomy (a controlled trial)

Antovska, Vesna; Basheska, Neli

doi:10.1016/j.maturitas.2005.05.012

Cited by 16 publications

(9 citation statements)

References 52 publications

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“…Vaginal conjugated equine estrogens (CEEs) cream or synthetic conjugated estrogens-A cream were evaluated in 1,064 women from eight RCTs, with doses ranging from 0.3 to 1.25 mg and with durations of 2 to 52 weeks. 4-11…”

Section: Resultsmentioning

confidence: 99%

Endometrial safety of low-dose vaginal estrogens in menopausal women: a systematic evidence review

Constantine¹,

Graham

Lapane

et al. 2019

Menopause

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Section: Resultsmentioning

confidence: 99%

Endometrial safety of low-dose vaginal estrogens in menopausal women: a systematic evidence review

Constantine¹,

Graham

Lapane

et al. 2019

Menopause

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“…In addition, perioperative estrogen therapy may promote vaginal wound healing after gynecologic surgery. [ 12 ] Vaginal estriol therapy is usually considered safe, with no endometrial effect even after 12 months of vaginal estriol treatment. [ 13 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 8 9 10 11 ] In addition, perioperative estrogen therapy may promote vaginal wound healing after gynecological surgery. [ 12 ] A comparison between vaginal cell cytology with and without vaginal estriol therapy in our cases shows thickening of the vaginal epithelium and eosinophilic well-maturated cells [ Figure 1 ].…”

Section: Introductionmentioning

confidence: 92%

Effect of vaginal estriol use in total laparoscopic hysterectomy with gonadotropin-releasing hormone agonist therapy

Hirata

Yoshida

Furuno

et al. 2018

Gynecol Minim Invasive Ther

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Study Objectives:The aim of this study is to evaluate the effects of vaginal estriol therapy in total laparoscopic hysterectomy (TLH) with gonadotropin-releasing hormone agonist (GnRH-a) treatment.Design:Retrospective analysis.Design Classification:Canadian Task Force classification II-2.Settings:Department of Gynecology, Yokohama City University Medical Center, Japan.Methods:We retrospectively investigated 50 fibroid cases that had TLH with preoperative GnRH-a treatment and compared the surgical outcome with or without vaginal estriol use (1mg). Estriol was used administered for two weeks before TLH.Measurements and Main Results:A total of 12 patients (27%) received vaginal estriol (1 mg) for 14 days before TLH. As a result of vaginal estriol treatment, there were no group differences in uterus size reduction with GnRH-a treatment (22% vs. 15%, P = 0.20), uterine removal time through the vagina (12.5 min vs. 18.5 min, P = 0.18), rate of vaginal dehiscence (3% vs. 0%, P = 0.76) or in the rate of perineal laceration (33% vs. 34%, P = 0.55).Conclusion:The use of vaginal estriol treatment before TLH with GnRH-a therapy did not improve surgical outcomes.

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“…En las mujeres posmenopáusicas, se puede utilizar crema vaginal de estrógenos para ayudar en la cicatrización de la herida (9).…”

Section: Discussionunclassified

Dehiscencia y evisceración vaginal recidivante: A propósito de un caso

Fuentes

Aguilar

Denaroso

et al. 2016

Rev. chil. obstet. ginecol.

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RESUMENLa dehiscencia de la cúpula vaginal, con o sin evisceración, es una complicación rara de la cirugía ginecológica. El principal factor de riesgo es el antecedente de una histerectomía, a lo que se añaden otros factores desencadenantes, entre los que destaca la atrofia vaginal. El diagnóstico de evisceración es fácil, al comprobar salida de material intestinal a través de la vagina, siendo más dificultoso el diagnóstico de dehiscencia, ya que puede acontecer con síntomas banales. El tratamiento supone una urgencia quirúrgica al existir riesgo de lesión intestinal y peritonitis, pudiéndose realizar diferentes vías de abordaje teniendo en cuenta sobre todo la clínica de la paciente y tras comprobar el estado del contenido eviscerado. Presentamos el caso de una paciente con varios factores de riesgo, que presentó dehiscencia de la cúpula vaginal con evisceración de intestino de manera reiterada, y a la que se le practicó tratamiento quirúrgico por diferentes vías de abordaje así como tratamiento médico.PALABRAS CLAVE: Dehiscencia cúpula vaginal, evisceración intestinal, histerectomía previa, atrofia vaginal, urgencia quirúrgica SUMMARYDehiscence of the vaginal vault with or without evisceration is a rare complication after gynaecological surgery. The main risk factor is a previous hysterectomy, with the addition of other trigger conditions, the most important is vaginal atrophy. The diagnosis of evisceration is easy by confirmation the loosing of intestinal contents through the vagina. Diagnosis of dehiscence is more difficult because its symptoms could be more generic. The treatment is an emergency surgery as there is a risk of intestinal injury and peritonitis. There could be different surgical approaches taking into consideration the patient's clinic symptoms and after checking the state of eviscerated tissues. We expose the case of a patient with several risk factors, who presented dehiscence of the vaginal vault with recurrent bowel evisceration, and who we performed surgical treatment by different approaches and medical treatment.KEY WORDS: Vaginal vault dehiscence, intestinal evisceration, prior hysterectomy, vaginal atrophy, surgical emergency REV CHIL OBSTET GINECOL 2016; 81(5): 393 -398

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Benefit and safety of 28-day transdermal estrogen regiment during vaginal hysterectomy (a controlled trial)

Cited by 16 publications

References 52 publications

Endometrial safety of low-dose vaginal estrogens in menopausal women: a systematic evidence review

Endometrial safety of low-dose vaginal estrogens in menopausal women: a systematic evidence review

Effect of vaginal estriol use in total laparoscopic hysterectomy with gonadotropin-releasing hormone agonist therapy

Dehiscencia y evisceración vaginal recidivante: A propósito de un caso

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