2017
DOI: 10.4172/2329-9126.1000315
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Benefits of Neoadjuvant Hypofractionated Radiotherapy in the Treatment of Locally Advanced Adenocarcinomas

Abstract: Background: The current treatment of locally advanced lower and middle rectum's adenocarcinoma is well codified. It is based on neoadjuvant radiotherapy (NRT) followed by surgical excision. However, two broad radiotherapy approaches are being debated: short course of hypo-fractionated radiation therapy "SRT" (5 GY × 5 days) and long course concomitant radio-chemotherapy "CRT" using higher radiation dose (45-50 GY over 5 weeks) combined with chemotherapy. The first approach allows taking care of about 4 times m… Show more

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