Benign and Malignant Skin Lesions: Dielectric Characterization, Modelling and Analysis in Frequency Band 1 to 14 GHz

Naqvi, Syed Akbar Raza; Mobashsher, Ahmed Toaha; Mohammed, Beadaa; Foong, Damien; Abbosh, Amin

doi:10.1109/tbme.2022.3199094

Cited by 17 publications

(8 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…By considering the data, our probe is in a good position and fits well with the goal considering also the resolution. It highlights some advantages of the approach presented in this paper: (i) the planar technology (based on printed circuit board (PCB)) allows easy link to other RF devices with a low cost sensor, (ii) as seen in [11], the frequency range used is well suited for skin/melanoma differentiation due to the clear permittivity difference and is easily accessible with most commercial vector network analyzers, (iii) the differential method permits to avoid the calibration step using reference materials and thus makes this tool easier to use for medical practitioners.…”

Section: Discussion On the Probe Specificationsmentioning

confidence: 94%

“…Besides, a commercial skin cancer detection tool based on impedance spectroscopy in the 1 kHz to 2.5 MHz frequency band has been presented in [10]. A low-cost solution is proposed in this paper with measurements performed over a lower frequency band on which the permittivity differences between normal skin and different lesion types are important; indeed, the permittivity variation is noticeable between different types of lesions in the 1-14 GHz frequency band according to the measurement results presented in [11]. Considering RF sensors, the open-ended coaxial probe is one of the most popular.…”

Section: Introductionmentioning

confidence: 98%

See 1 more Smart Citation

Design and characterization of a broadband PCB-based coaxial sensor for permittivity screening in skin cancer detection applications

Fritiss,

Poulichet,

Takhedmit

et al. 2023

Meas. Sci. Technol.

View full text Add to dashboard Cite

Broadband dielectric spectroscopy is nowadays considered as a useful non-destructive diagnostic tool for biomedical applications like glucose monitoring, hydration level measurement, and cancer tissue examination. Depending on their composition and physiological state, biological tissues have different dielectric characteristics and studies on melanoma have revealed that the lesion site's skin permittivity degree changes depending on the malignancy of the lesion. The complex permittivity of suspicious areas must therefore be imaged with spatial resolution consistent with the small dimensions of these surfaces in order to correctly detect and characterize the lesion site. The variety of skin qualities for various individuals and physiological situations (such as temperature, humidity), however, makes it difficult to build a sensitive sensor capable of constantly detecting minor fluctuations in permittivity. In order to identify various types of cancers in their early stages with a good agreement between simulated and measured results, this work proposes the design of a unique microwave sensor that can precisely detect alterations in cutaneous permittivity between 1 and 6 GHz.

show abstract

Section: Discussion On the Probe Specificationsmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 98%

Design and characterization of a broadband PCB-based coaxial sensor for permittivity screening in skin cancer detection applications

Fritiss,

Poulichet,

Takhedmit

et al. 2023

Meas. Sci. Technol.

View full text Add to dashboard Cite

show abstract

“…Moreover, an image of the target area cannot be reconstructed. Attempts to detect malignancy in higher frequencies (microwave, millimeter-wave, and near-infrared) have also been made (Mehta et al 2006, Bodén et al 2013, Taeb et al 2013, Mirbeik-Sabzevari et al 2017, Mohammed et al 2018, Mirbeik-Sabzevari and Tavassolian 2019, Mirbeik et al 2022, Naqvi et al 2022, but the hardware can be complex and bulky. While handheld vector network analyzers (VNA) can be used, as done in Naqvi et al (2022), they bear similar limitations to the Nevisense pen.…”

Section: Introductionmentioning

confidence: 99%

A non-invasive approach to skin cancer diagnosis via graphene electrical tattoos and electrical impedance tomography

Lee,

Johnson,

Denton

et al. 2024

Physiol. Meas.

View full text Add to dashboard Cite

Objective: Making up one of the largest shares of diagnosed cancers worldwide, skin cancer is also one of the most treatable. However, this is contingent upon early diagnosis and correct skin cancer-type differentiation. Currently, methods for early detection that are accurate, rapid, and non-invasive are limited. However, literature demonstrating the impedance differences between benign and malignant skin cancers, as well as between different types of skin cancer, show that methods based on impedance differentiation may be promising. Approach: In this work, we propose a novel approach to rapid and non-invasive skin cancer diagnosis that leverages the technologies of difference-based electrical impedance tomography (EIT) and graphene electronic tattoos (GETs). Main Results: We demonstrate the feasibility of this first-of-its-kind system using both computational numerical and experimental skin phantom models. We considered variations in skin cancer lesion impedance, size, shape, and position relative to the electrodes and evaluated the impact of using individual and multi-electrode GET (mGET) arrays. The results demonstrate that this approach has the potential to differentiate based on lesion impedance, size, and position, but additional techniques are needed to determine shape. Significance: In this way, the system proposed in this work, which combines both EIT and GET technology, exhibits potential as an entirely non-invasive and rapid approach to skin cancer diagnosis.

show abstract

“…These studies involve various types of tissues, including breast tissues [12][13][14][15], in vitro cell lines derived from both normal and tumorous breast tissues [16,17], colon tissues [18], and liver tissues [9]. Additionally, OECPs have been used in the identification of hepatic malignancies [19,20], aided by machine-learning techniques, as well as in the analysis of skin lesions [21]. Current probes present on the market have various limitations [7], such as requiring multiple probes for broadband characterization, high costs, and the complexity of the calibration process, which involves SOL (short, open, and load) systems.…”

Section: Introductionmentioning

confidence: 99%

Open-Ended Coaxial Probe for Effective Reconstruction of Biopsy-Excised Tissues’ Dielectric Properties

Canicattì,

Fontana,

Barmada

et al. 2024

Sensors

View full text Add to dashboard Cite

Dielectric characterization is extremely promising in medical contexts because it offers insights into the electromagnetic properties of biological tissues for the diagnosis of tumor diseases. This study introduces a promising approach to improve accuracy in the dielectric characterization of millimeter-sized biopsies based on the use of a customized electromagnetic characterization system by adopting a coated open-ended coaxial probe. Our approach aims to accelerate biopsy analysis without sample manipulation. Through comprehensive numerical simulations and experiments, we evaluated the effectiveness of a metal-coating system in comparison to a dielectric coating with the aim for replicating a real scenario: the use of a needle biopsy core with the tissue inside. The numerical analyses highlighted a substantial improvement in the reconstruction of the dielectric properties, particularly in managing the electric field distribution and mitigating fringing field effects. Experimental validation using bovine liver samples revealed highly accurate measurements, particularly in the real part of the permittivity, showing errors lower than 1% compared to the existing literature data. These results represent a significant advancement for the dielectric characterization of biopsy specimens in a rapid, precise, and non-invasive manner. This study underscores the robustness and reliability of our innovative approach, demonstrating the convergence of numerical analyses and empirical validation.

show abstract

Benign and Malignant Skin Lesions: Dielectric Characterization, Modelling and Analysis in Frequency Band 1 to 14 GHz

Cited by 17 publications

References 44 publications

Design and characterization of a broadband PCB-based coaxial sensor for permittivity screening in skin cancer detection applications

Design and characterization of a broadband PCB-based coaxial sensor for permittivity screening in skin cancer detection applications

A non-invasive approach to skin cancer diagnosis via graphene electrical tattoos and electrical impedance tomography

Open-Ended Coaxial Probe for Effective Reconstruction of Biopsy-Excised Tissues’ Dielectric Properties

Contact Info

Product

Resources

About