Benign Breast Disorders

Weaver, Micaela; Stuckey, Ashley

doi:10.1016/j.ogc.2021.11.003

Cited by 16 publications

(17 citation statements)

References 36 publications

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“…26 They commonly present in premenopausal women and have a similar clinical presentation to fibroadenomas, averaging 4 to 5 cm in size. 27 , 28 Phyllodes tumors often have a round, lobulated appearance with partially indistinct or circumscribed margins on mammography and ultrasonography. Cystic features are commonly seen in malignant variants.…”

Section: Lesions and Management Strategiesmentioning

confidence: 99%

Prevalence, Impact, and Diagnostic Challenges of Benign Breast Disease: A Narrative Review

Fraker,

Clune,

Sahni

et al. 2023

IJWH

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Benign breast diseases, which are commonly seen in clinical practice, have various clinical presentations and implications, as well as management strategies. This article describes common benign breast lesions, presentations of these lesions, and typical radiographic and histologic findings. Also included in this review are the most recent data and guideline-based recommendations for the management of benign breast diseases at diagnosis, including surgical referral, medical management, and ongoing surveillance.

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Section: Lesions and Management Strategiesmentioning

confidence: 99%

Prevalence, Impact, and Diagnostic Challenges of Benign Breast Disease: A Narrative Review

Fraker,

Clune,

Sahni

et al. 2023

IJWH

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“…Mastalgia (also known as mammalgia or mastodynia) is a medical term described mainly as breast pain during a female lifetime (10,22). This condition has multifaceted and inhomogeneous clinical features.…”

Section: Features Of Different Types Of Mastalgiamentioning

confidence: 99%

“…Mastalgia most often appears in premenopausal and perimenopausal women, but postmenopausal women can also, but rarely, experience it. Breast pain can range from minor discomfort to severely disabling pain, and it can occur continuously or intermittently throughout the day (22,23).…”

Section: Features Of Different Types Of Mastalgiamentioning

confidence: 99%

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The mechanisms underlying the role of Vitex agnus-castus in mastalgia

ZEQIRI¹,

DERMAKU-SOPJANI²,

SOPJANI³

2022

BLL

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Medicinal plants exert therapeutic effects or have benefi cial healing functions on the human or animal body. Medicinal plants are widely used in traditional medicine as an interesting alternative and/or complementary to science-based medicine. Compared to chemical drugs, medicinal plants have a lower risk of side effects, are eco-friendly, and have cost-effective production. This encouraged researchers to extensively exploit them for their therapeutic use. One of the most well-known medicinal plants is Vitex agnus-castus L., which belongs to the Verbenaceae family. This shrub tree is mainly grown in tropical and sub-tropical regions. The parts of VAC, especially berries and leaves, contain essential oils, fl avonoids, and diterpenes. Many medical benefi ts of VAC have already been reported, including mastalgia, regulating menstrual cycles and premenstrual complaints, and infertility. Respiratory and cardiovascular effects are also reported. In this review, we will analyze and characterize the known roles of VAC in mastalgia, as well as the mechanism of action reported in in vitro and/or in vivo studies, and show the potential for alternative therapeutic uses in mastalgia, also known as breast pain (Fig. 2, Ref. 40).

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“…Increased water retention in the breast and ductal ectasia has been suggested to be the principal causes of CM [ 4 ]. Breast volume may increase by more than 100 mL during the luteal phase of the menstrual cycle due to the hormonal stimulation of breast parenchyma [ 5 , 6 ]. In addition, breast pain was found positively associated with the degree of ductal dilatation [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of acupuncture in the treatment of cyclic mastalgia: a study protocol for a randomized controlled trial

Wang²,

Shen³

et al. 2022

BMC Complement Med Ther

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Background About 68% of women aged 18–44 years have experienced cyclic mastalgia (CM), which occurs during the luteal phase of the menstrual cycle when elevated hormone levels induce greater breast gland thickness. CM has a moderate-to-severe impact on a woman’s quality of life. Prior research has suggested that acupuncture may be beneficial for breast pain relief. In this study, we investigate the effectiveness of manual acupuncture (MA) in the treatment of CM compared with that of sham acupuncture (SA). Methods This is a multicenter, randomized, controlled trial. A total of 108 eligible CM patients will be randomly assigned to either MA (n = 54) or SA (n = 54) group using a 1:1 ratio and a stratified, blocked randomization. Acupuncture will be performed two weeks prior to menstruation and discontinued when menses begins. In both the MA and SA group, participants will be given acupuncture three times per week for 2 weeks per menstrual cycle for three consecutive menstrual cycles, encompassing a total of 18 sessions. The primary outcome will be the change in the average daily Breast Pain Visual Analog Scale (VAS-BP) over the first two weeks of menstruation from baseline to endpoints. The number of nominal days of breast pain (NDBP) two weeks before menstruation, World Health Organization Quality-of-Life Scale-Short Form scores, global patient assessment, breast glandular-section thickness, and breast-duct width three days before menstruation will also be measured as secondary outcomes. Discussion This prospective randomized trial will help evaluate the efficacy of acupuncture in treating CM. The results of this study will provide evidence of the therapeutic effectiveness of acupuncture on CM. Trial registration ClinicalTrials.gov Identifier: NCT05408377, registered on June 7, 2022.

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Benign Breast Disorders

Cited by 16 publications

References 36 publications

Prevalence, Impact, and Diagnostic Challenges of Benign Breast Disease: A Narrative Review

Prevalence, Impact, and Diagnostic Challenges of Benign Breast Disease: A Narrative Review

The mechanisms underlying the role of Vitex agnus-castus in mastalgia

Effectiveness of acupuncture in the treatment of cyclic mastalgia: a study protocol for a randomized controlled trial

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