Benign breast lesions in Bayelsa State, Niger Delta Nigeria: a 5 year multicentre histopathological audit

Uwaezuoke, Stanley Chibuzo; Udoye, Ezenwa Patrick

doi:10.11604/pamj.2014.19.394.5717

Cited by 15 publications

(17 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The pattern of breast diseases and their etiology varies among different countries and ethnic groups (Aslam et al, 2013).In this study the pattern of breast diseases among women attending breast diagnosing center in Erbil city /Iraq had been identified, thus nearly two thirds (63%) of them were diagnosed as benign breast diseases while 13.2% found to have breast cancer, these results were nearly similar to two studies conducted in Nigeria (Mayun, Pindiga, & Babayo, 2008;Uwaezuoke & Udoye, 2014) while other studies conducted in India (Rasheed et al, 2014) and Tanzania (Chalya et al, 2016) showed slightly higher proportions of both benign breast diseases; (80.7%), (80,4%) and that of breast cancer (22.2 %), (19.6%) respectively. This could be related to the demographic characteristics of the selected sample since only (17%) of the women in this study were above 50 years.…”

Section: Discussionsupporting

confidence: 83%

“…Gupta, Goyal, & Sharma, 2015), in Nigeria (45.6%) (Uwaezuoke & Udoye, 2014) and (52%) in a study done by (Naveen, Mukherjee, & Mahajan, 2013). While the second most common benign breast disease in this study found to be breast cyst (8.6 %), a study done in Africa (Femi, Nnaetio, & Ayedima , 2016) showed that breast cyst was the 5 th benign disease but with a proportion of (14.0%).…”

Section: Discussionmentioning

confidence: 45%

“…Fibrocystic changes in the current study ranked as the 5 th most common BBD (3.2%) compared to other studies conducted in Pakistan (Memon et al 2007) and in Jamaica (Shirley et al, 2008) both reported fibrocystic changes as the most common BBD in their series. while other study done in Nigeria found that fibrocystic breast changes to be the 2 nd most common BBD (26.3%) (Uwaezuoke & Udoye, 2014).…”

Section: Discussionmentioning

confidence: 79%

See 2 more Smart Citations

Patterns of Breast Diseases Among Women Attending Breast Diseases Diagnosing Center in Erbil City/Iraq

Yousif¹,

Yacoub²

2018

GJHS

View full text Add to dashboard Cite

Background and Objectives: Breast diseases in women, whether benign or malignant, are very commonly encountered. The pattern of breast diseases varies within countries. The aim of this study was to identify the patterns of breast diseases and their association with different variables in women attending breast diseases diagnosing center in Erbil city/Iraq. Material and Methods:A cross-sectional study conducted at breast diseases diagnosing center in Erbil city from 1 st of April till 1 st of December /2017. A random sample of 500 women of all age groups and with complete records was recruited. The women were classified according to their final diagnosis into 3 categories: normal, benign and malignant breast disease. The level of significance was <0.05. Results:Benign breast diseases diagnosed among (63%) women while malignant breast diseases comprised (13.2%).The most common presentation was mastalgia and mass (39.2%), mastalgia (37.6%), and mass alone (23.2%). Fibro-adenoma (26.2%) was the commonest benign condition with highest incidence (76.9%) in age group less than 20 years. Malignant breast diseases were increasing with age. Benign breast disease associated (p <0.001) with Nulliparity. Breast cancer reported (p <0.001) more among lactating women. Conclusions:Benign conditions are the most common diagnosis affecting mainly younger women. Breast cancer though diagnosed less frequently and affecting older age groups, yet its seriousness mandating a thorough assessment of women of different presentations especially that of mass alone or with mastalgia.

show abstract

Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 45%

Section: Discussionmentioning

confidence: 79%

See 1 more Smart Citation

Patterns of Breast Diseases Among Women Attending Breast Diseases Diagnosing Center in Erbil City/Iraq

Yousif¹,

Yacoub²

2018

GJHS

View full text Add to dashboard Cite

show abstract

“…Benign non proliferative lesions of the breast were the commonest lesions 159(74.0%) in females in our study. Of these lesions Fibroadenoma (76%),is the commonest benign non-proliferative lesion, mirrowing other Nigerian studies [14,[32][33][34][35][36]. Other benign lesions in the female breast in our study were Periductal mastitis, lipomas, fat necrosis, tubular adenoma, Juvenile papillomatosis, granulomatous mastitis, granulation tissue, benign phyllodes, acute mastitis, lymphocytic mastitis, granular cell myoblastoma, lactating adenoma and myofibroblastoma all of which account for less than 30 percent.…”

Section: Discussionsupporting

confidence: 80%

Prevalence of Benign Breast Lesions, Epithelial Proliferations with or without Atypia in Calabar-A Retrospective Review

Ebughe

Ugbem

Ushie

et al. 2019

IJTDH

View full text Add to dashboard Cite

Aims: The aim of this study is to find out the prevalence of benign breast lesions and proliferative lesions which are associated with increase risk of breast cancer. This is aimed at influencing the hospital policy on mammographic screening. Study Design: Descriptive retrospective study involving a trend analysis of benign breast lesion, proliferative analysed in the surgical pathology unit of the University of Calabar Teaching Hospital between 1st of January 2012 to October 31st 2014. Place and Duration of Study: Pathology Department of the University of Calabar Teaching Hospital. The study was carried out between March and April 2019. Methodology: Descriptive retrospective study of trend analysis of benign and proliferative breast lesions over the period with literature review. Results: Two hundred and seventeen 217 patients consisting of seven males and two hundred and ten females with a female: Male ratio of 1:0.04. Mean age was 26.4 ± 10.0 years, ranging from 10 to 70 years, with 21-30 (94, 43.5%), as the predominant age and less than 21 years (70, 32.4%) as the second common age group. Seventy four percent of (74%) of the breast lesions were benign non proliferative lesions while 26% were proliferative breast lesions. Of the proliferative lesions, five or 8.9% of the proliferative or 2.33% of the lesions were atypical ductal hyperplasia’s which have a high risk of progression to cancer. Conclusion: Proliferative breast lesions and the premalignant lesions of the breast are not commonly reported in Calabar. An upscale of population screening and mammographic services may improve their yield which will help prevent some invasive breast cancers.

show abstract

“…Understanding indicators of HMG in middle-aged women play an important part in public health and clinical implications. Researches have identified multiple risk factors for HMG 3 , such as late age at menopause 4,5 , nulliparity 4,5 , lacking breastfeeding 6 , high-level education 7 and family history of breast cancer 8 . Nevertheless, etiology of HMG remains largely unknown.…”

Section: Introductionmentioning

confidence: 99%

The potential interaction of hereditary and reproductive factors in the etiology of mammary gland hyperplasia: a case-control study

gao

Liu

Fan

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: Family history of breast cancer and female reproductive factors may work together to influence hyperplasia of mammary gland (HMG) risk. However, the association with HMG risk is poorly characterized and might be important to understand the causation of HMG.Methods: A total of 1881 newly diagnosed HMG cases and 1900 controls were recruited between 2012 and 2017. We collected each participant's demographic characteristics, female reproductive factors and family history of breast cancer. A multi-analytic strategy combining unconditional logistic regression, multifactor dimensionality reduction (MDR) and crossover approaches were applied to systematically identify the interactions of family history of breast cancer and reproductive factors on HMG susceptibility.Results: In MDR analysis, high-order interactions among education level, breastfeeding duration and family history of breast cancer were identified among women (OR=7.069, 95%CI: 6.080-8.219). Similarly, in crossover analysis, compared with individuals having low education level and no family history of breast cancer, HMG risk increased significantly for those having high education level and family history of breast cancer (OR=36.389, 95%CI: 11.469-115.451), similar additive interaction effect was observed among short breastfeeding duration women (OR=27.699, 95%CI: 3.730-205.699).Conclusion: This study suggests high-order interactions of high education level, short breastfeeding duration and family history of breast cancer may synergistically increased HMG risk.

show abstract

Benign breast lesions in Bayelsa State, Niger Delta Nigeria: a 5 year multicentre histopathological audit

Cited by 15 publications

References 15 publications

Patterns of Breast Diseases Among Women Attending Breast Diseases Diagnosing Center in Erbil City/Iraq

Patterns of Breast Diseases Among Women Attending Breast Diseases Diagnosing Center in Erbil City/Iraq

Prevalence of Benign Breast Lesions, Epithelial Proliferations with or without Atypia in Calabar-A Retrospective Review

The potential interaction of hereditary and reproductive factors in the etiology of mammary gland hyperplasia: a case-control study

Contact Info

Product

Resources

About