Chondroblastoma is a benign cartilaginous lesion of bone. When occurring in a position juxtaposed to articular cartilage, treatment is directed at removal of the tumor with preservation of the articular cartilage. In this case, a chondroblastoma of the talus with erosion into the articular cartilage was treated with transfer of an osteochondral autograft from the ipsilateral femoral condyle. At two-year follow-up, the patient was symptom free and magnetic resonance imaging revealed complete incorporation of the graft. This case is presented as a representative example of osteochondral autograft transfer surgery (OATS) for the treatment of chondroblastoma.