Benign Cutaneous Polyarteritis Nodosa

Minkowitz, Gerald

doi:10.1001/archderm.1991.01680090084009

Cited by 49 publications

(10 citation statements)

References 13 publications

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“…On the other hand, in two reports of CPN, none of the patients had a HBV infection in 47 cases 6 or in 16 cases 3 . Only one report 12 showed that four of nine patients with CPN had serological evidence of a HBV infection. In our study, HBV antigens, which were assessed in 14 of the 16 patients, were negative.…”

Section: Discussionmentioning

confidence: 94%

Cutaneous polyarteritis nodosa: A report of 16 cases with clinical and histopathological analysis and a review of the published work

Ishiguro

Kawashima

2010

The Journal of Dermatology

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Sixteen cases of cutaneous polyarteritis nodosa referred to our Department from 1985 to 2003 were studied clinically and histopathologically. Laboratory data, treatments and clinical courses were also evaluated retrospectively. All cases had nodules and/or indurated erythemas on their lower extremities. All cases showed necrotizing vasculitis of small muscular arteries in the subcutaneous tissues and/or occlusion of those arteries histopathologically. Fifteen cases also had accumulation of plasma protein in vessels of the dermis and subcutaneous tissues. Laboratory data showed high activity of platelets and coagulation in some cases. Eleven cases had been effectively treated with non-steroidal anti-inflammatory drugs. Eight cases were observed for at least 5 years (the longest for approximately 19 years) and had good prognoses and no systemic involvement. Cutaneous polyarteritis nodosa seems to be a benign disease, and differs from systemic polyarteritis nodosa although their histopathological features are common. Cutaneous polyarteritis nodosa might involve local dysfunction of the circulation from the dermis to the subcutaneous area. A review of the published work shows that the cause(s) of most cases of cutaneous polyarteritis nodosa is unknown, that no controlled trials for treatment of cutaneous polyarteritis nodosa compared to polyarteritis nodosa have been reported, and that no definitively effective therapy for cutaneous polyarteritis nodosa has been established.

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Section: Discussionmentioning

confidence: 94%

Cutaneous polyarteritis nodosa: A report of 16 cases with clinical and histopathological analysis and a review of the published work

Ishiguro

Kawashima

2010

The Journal of Dermatology

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“…In this study, all pa-tients were followed up for an average of seven years (six months to 17 years) (8). In the retrospective study of Minkowitz et al, seven of nine cases were reported to have had evidence of systemic involvement in four month to 14 year follow-up periods (9).…”

Section: Discussionmentioning

confidence: 90%

Three Cases of Polyarteritis Nodosa Cutanea and a Review of the Literature

Gushi

Hashiguchi

Fukumaru

et al. 2000

The Journal of Dermatology

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We describe three cases of polyarteritis nodosa cutanea (PNC) showing necrotizing arteritis and only cutaneous lesions without systemic symptoms or visceral involvement for eleven, six, and three years after the onset of the disease. Since it was first described, there has been continuous controversy as to whether PNC progresses to systemic PN. Some cases have been described which had begun with a cutaneous lesion and progressed to the systemic form 19 and 18 years after the onset of the disease, so we believe that long term follow-up of this disease is essential.

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“…Presenting symptoms in adults include fever, myalgias, arthralgias, neuralgias, and neuropathy 9,12,14 . Typically, the disease is limited to the skin, muscles, and joints 19 . Mononeuritis can present as decreased reflexes and paresthesias 12 .…”

Section: Clinical Findings: Cpanmentioning

confidence: 99%

“…The hallmark cutaneous finding in CPAN is tender nodules 0.5–2 cm on the foot, ankle, and lower legs 12,13,19 . The lesions turn bluish as they heal and yet will recur in the same location 2,19 .…”

Section: Clinical Findings: Cpanmentioning

confidence: 99%

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Polyarteritis Nodosa and Cutaneous Polyarteritis Nodosa

Herbert

Russo

2003

Skinmed

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Cutaneous vasculitis can present with a variety of lesions and associated symptoms. It is important for the clinician to be able to recognize vasculitis lesions and know when to pursue further laboratory studies that will determine the extent of the disease process in a patient. This review compares and contrasts polyarteritis nodosa with its cutaneous counterpart. The diagnostic workup and management of these two entities as well as the overall approach to a patient with a possible vasculitic condition are emphasized.

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Benign Cutaneous Polyarteritis Nodosa

Cited by 49 publications

References 13 publications

Cutaneous polyarteritis nodosa: A report of 16 cases with clinical and histopathological analysis and a review of the published work

Cutaneous polyarteritis nodosa: A report of 16 cases with clinical and histopathological analysis and a review of the published work

Three Cases of Polyarteritis Nodosa Cutanea and a Review of the Literature

Polyarteritis Nodosa and Cutaneous Polyarteritis Nodosa

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