Benign Esophageal Obstruction Due to Radiation Esophagitis

Yokoi, Keigo; Hosoda, Kei; Katada, Natsuya; Yamashita, Keishi; Moriya, Hiromitsu; Mieno, Hiroaki; Ohbu, Makoto; Watanabe, Masahiko

doi:10.5833/jjgs.2016.0137

Cited by 2 publications

(2 citation statements)

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“…Low-dose of radiation is easy to cause the esophageal ulcer/stenosis in the patient performed chemoradiotherapy even if chemotherapy and radiotherapy are heterochrony [ 15 - 17 ]. The combination of SBRT and vascular endothelial growth factor inhibitor (VEGFI) for HCC increases bowel toxicity [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…There are few cases which had esophageal ulcer/stenosis caused by radiotherapy for non-esophageal cancer, such as lung cancer [ 3 , 19 , 22 ], laryngopharynx cancer [ 19 , 23 , 24 ], malignant lymphoma [ 15 ], and bone metastases of breast cancer [ 16 ]. Gastroduodenal ulcer and gastritis often occur as a complication of the radiotherapy for HCC [ 25 , 26 ].…”

Section: Discussionmentioning

confidence: 99%

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A Case of Refractory Esophageal Ulcer Caused by Radiotherapy for Hepatocellular Carcinoma

et al. 2021

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A 77-year-old man who underwent radiotherapy for hepatocellular carcinoma 6 months prior consulted for esophageal obstruction. Esophagogastroduodenoscopy revealed an esophageal ulcer caused by radiotherapy for hepatocellular carcinoma. He was treated with dietary counseling and vonoprazan. After 9 months, the ulcer improved but a moderate stenosis remained. Several factors such as high fraction size, history of chemotherapy, and stress associated with food intake might involve in the development of a radiation-associated ulcer. Opportunities to choose radiotherapy for hepatocellular carcinoma may increase, so we hypothesize that esophageal ulcers might be a complication that should be noted associated with this therapy.

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Section: Discussionmentioning

confidence: 99%