Benign Familial Neonatal Seizures

Pettit, Ross E.; Fenichel, Gerald M.

doi:10.1001/archneur.1980.00500500077012

Cited by 52 publications

(10 citation statements)

References 7 publications

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“…In the previously reported cases of BFNC, the predominant seizure types were reported to be multifocal clonic, focal clonic, and generalized tonicclonic, sometimes with apneic spells (Plouin, 1985; Rett and Teubel, 1964Bjerre and Corelius, 1968GoutiBres, 1977Carton, 1978Quattlebaum, 1979Pettit and Fenichel, 1980Tibbles, 1980 Family 1 Family 2 Family 3…”

Section: Mmentioning

confidence: 99%

“…In 1968, Bjerre and Corelius reported a pedigree with a high incidence of neonatal convulsions with good prognosis, which they called benign familial neonatal convulsions (BFNC). Additional families have since been reported (Goutieres, 1977;Carton, 1978;Quattlebaum, 1979;Pettit and Fenichel, 1980;Tibbles, 1980;Watanabe, 1981;Dobrescu and Larbrisseau, 1982;Giacoia, 1982;Takebe et al, 1983;Crispen and Kelly, 1985;Shevell et al, 1986;Cunniff et al, 1988;Wakai et al, 1990;Webb and Bobele 1990; Camfield et al, 1991;Ryan et al, 1991;Malafosse et al, 1992), and BFNC has been recognized as a distinct epileptic syndrome (Plouin, 1985;Commission, 1989).…”

mentioning

confidence: 99%

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Infantile Spasms in One Member of a Family with Benign Familial Neonatal Convulsions

Mori¹,

Yano²,

Hashimoto

1993

Epilepsia

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Seven members of two generations experienced benign familial neonatal convulsions (BFNC) in the neonatal period and/or early infancy. All but 1 family member had a good prognosis. One family member with infantile spasms (IS) was delivered by cesarean section at 37 weeks gestation. Birth weight (2,562 g) was slightly lower than that of other family members. At age 20 days, adversive seizures started. At age 1 month, 10 days, she developed complex partial seizures (CPS) and IS. Interictal EEG showed hypsarrhythmia. Biochemical investigations and head magnetic resonance imaging (MRI) scan showed no abnormalities. Treatment with valproate (VPA) and carbamazepine (CBZ) stopped the seizures, and she had no seizures after age 3 months. Psychomotor development was moderately delayed at 8 months. This is the first reported case of a severe epilepsy, IS, in association with BFNC.

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Section: Mmentioning

confidence: 99%

mentioning

confidence: 99%

Infantile Spasms in One Member of a Family with Benign Familial Neonatal Convulsions

Mori¹,

Yano²,

Hashimoto

1993

Epilepsia

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“…In 1964, Rett and Teubel reported the first family with a disorder presently referred to as "benign familial neonatal seizures." Since then 15 additional families have been described [Bjere and Corelius, 1968;Carton, 1978;Giacoia, 1982;Goutikres, 1977;Gross et al, 1980;Herranz and Arce, 1979;Kaplan and Lacey, 1983;Pettit and Fenichel, 1980;Quattlebaum, 1979;Rose and Lombroso, 1970;Tibbles, 19801. Thus, this disorder is commoner than realized and is probably still underrecognized.…”

Section: Introductionmentioning

confidence: 99%

Familial neonatal and infantile seizures: An autosomal‐dominant disorder

Zonana

Silvey

Strimling³

1984

Am. J. Med. Genet.

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Familial neonatal seizures are an important and probably underrecognized disorder. A family with six affected individuals in three generations was evaluated and their clinical characteristics were compared with those of 15 families previously reported in the literature. An analysis of the 116 affected individuals uncovered a typical clinical picture of onset of seizures by 2 to 8 days of life in an otherwise healthy appearing infant, and cessation of seizures by 1 to 6 months. Results of diagnostic evaluations were normal, and the pathogenesis of the disorder is still unclear. Long-term neurodevelopmental outcome was normal except for an increased rate (11%) of subsequent seizures in childhood or as an adult. The disorder was inherited as an autosomal-dominant trait with a high degree of penetrance.

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“…Benign familial neonatal convulsions are rare disorder of autosomal dominant inheritance with incomplete penetrance, usually occurs in the first week of life after an initial seizurefree period. The neonate is otherwise healthy but with family history of neonatal seizures (58)(59)(60) . The seizures are focal clonic or focal tonic, sometimes associated with apnoeic spells or eye deviation to one side.…”

Section: Causesmentioning

confidence: 99%

Neonatal Seizures

Al-Zwaini¹

2011

Epilepsy in Children - Clinical and Social Aspects

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Benign Familial Neonatal Seizures

Cited by 52 publications

References 7 publications

Infantile Spasms in One Member of a Family with Benign Familial Neonatal Convulsions

Infantile Spasms in One Member of a Family with Benign Familial Neonatal Convulsions

Familial neonatal and infantile seizures: An autosomal‐dominant disorder

Neonatal Seizures

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