Benign Focal Lesions of the Liver

Trotter, James F.; Everson, Gregory T.

doi:10.1016/s1089-3261(05)70152-5

Cited by 113 publications

(67 citation statements)

References 129 publications

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“…Some of these hemangiomas have estrogen receptors, and accelerated growth has been observed during estrogen influence during puberty, pregnancy, oral contraceptive use, and with androgen treatment. 26,46,48,49 Growing tumors are mainly seen in women. 49,50 In summary, for typical hemangiomas in an asymptomatic patient without risk factors for malignancy, conventional B-mode ultrasound is sufficient and no further imaging method is recommended.…”

Section: Discussionmentioning

confidence: 99%

Contrast‐enhanced ultrasound of histologically proven liver hemangiomas†

et al. 2007

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Differentiation of small and atypical hemangiomas from other hepatic masses using imaging methods can be difficult, especially in patients with underlying malignant disease. Therefore, contrast-enhanced ultrasound was assessed in patients with histologically confirmed hemangiomas with respect to contrast-enhancing kinetics and tumor characteristics. In 58 patients with indeterminate hepatic lesions demonstrated with at least 2 imaging methods (ultrasound/computed tomography/magnetic resonance imaging), ultrasound-guided liver biopsy revealed hemangioma. In all patients a hepatic neoplasm had been suspected because of underlying malignant disease (n ‫؍‬ 41), liver cirrhosis (n ‫؍‬ 15), or growth of the lesion (n ‫؍‬ 2). All patients underwent nonlinear, low mechanical index real-time contrast-enhanced ultrasound scanning with bolus injections of SonoVue. Peripheral nodular arterial enhancement was detected in 43 patients (74%), whereas the typical metastatic peripheral rim-like enhancement was not observed at all. Strong homogenous arterial enhancement was found in 9 of 58 (16%) patients. In 6 patients (10%), the arterial contrast enhancement pattern could not be determined because of the very small size of the lesions or fibrotic nodules. Forty-five (78%) of the hemangiomas showed homogenous centripetal filling within 180 seconds. Conclusion: Contrast-enhanced ultrasound demonstrates typical hemangioma imaging characteristics, that is, peripheral nodular contrast enhancement and iris-diaphragm sign in a high percentage of patients with undetermined lesions. This technique may therefore improve noninvasive functional characterization and differentiation of hemangiomas. (HEPATOLOGY 2007;45:1139-1145

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Section: Discussionmentioning

confidence: 99%

Contrast‐enhanced ultrasound of histologically proven liver hemangiomas†

et al. 2007

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“…Liver hemangiomas are the most common benign tumors of the liver, with an estimated prevalence of 3%-20% [1][2][3] . Most of them are small in size (< 4 cm in diameter) and asymptomatic and are discovered incidentally during screening tests by modern diagnostic procedures.…”

Section: Introductionmentioning

confidence: 99%

Successful liver resection in a giant hemangioma with intestinal obstruction after embolization

Zhou¹,

Huang²,

Wu³

et al. 2013

WJG

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Hepatic hemangiomas are the most common benign tumor of the liver. Most hepatic hemangiomas remain asymptomatic and require no treatment. Giant hepatic hemangiomas with established complications, diagnostic uncertainty and incapacitating symptoms, however, are generally considered an absolute indication for surgical resection. We present a case of a giant hemangioma with intestinal obstruction following transcatheter arterial embolization, by which the volume of the hemangioma was significantly reduced, and it was completely resected by a left hepatectomy. A 21-yearold Asian man visited our hospital for left upper quadrant pain. Examinations at the first visit revealed a left liver hemangioma occupying the abdominal cavity, with a maximum diameter of 31.5 cm. Embolization of the left hepatic artery was performed and confirmed a decrease in its size. However, the patient was readmitted to our hospital one month after embolization for intestinal obstruction. A left hepatectomy was completed through a herringbone incision, and safely removed a giant hemangioma of 26.5 cm × 19.5 cm × 12.0 cm in size and 3690 g in weight. Pre-operative arterial embolization is effective for reducing tumor size, but a close follow-up to decide the time for hepatectomy is important.

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“…Most hemangioma are asymptomatic, detected incidentally on imaging of abdomen for unrelated reasons [8]. Pain related to an uncomplicated hemangioma is usually due to associated disorders e.g., peptic ulcer.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous Rupture of a Giant Hepatic Hemangioma-Report of a Case

Gupta

Agarwal

Acharya³

2011

Indian J Surg

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Hemangioma is the commonest benign hepatic neoplasm. Most cases are asymptomatic. Spontaneous rupture is rare (1-4%). Only 34 cases have been reported in adults. None had history of trauma. We report a case, the first from India of spontaneous rupture of a giant hepatic hemangioma, in a 25 year old male presenting with acute abdomen. He underwent right hepatectomy. Histopathology suggested cavernous hemangioma.

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Benign Focal Lesions of the Liver

Cited by 113 publications

References 129 publications

Contrast‐enhanced ultrasound of histologically proven liver hemangiomas†

Contrast‐enhanced ultrasound of histologically proven liver hemangiomas†

Successful liver resection in a giant hemangioma with intestinal obstruction after embolization

Spontaneous Rupture of a Giant Hepatic Hemangioma-Report of a Case

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