Benign Glandular Inclusions in Parotid Nerve

Cramer, Stewart F.; Heggeness, Lucille M.

doi:10.1093/ajcp/90.2.220

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Reexcision Pni1

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Cited by 8 publications

(4 citation statements)

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“…Benign inclusions in the perineural space simulating PNI have been reported in prostate, 31–33 parotid nerve, 34 oral, 35 and breast 36 cancers. It is likely that the same phenomenon occurs in the skin.…”

Section: Reexcision Pnimentioning

confidence: 97%

Perineural Invasion

Dunn

Morgan

Beer

2009

Dermatologic Surgery

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We propose the following definition for the minimum histopathologic criteria required to make a diagnosis of PNI: "In the presence of a malignancy, PNI may be diagnosed according to the observation of cytologically malignant cells in the perineural space of nerves. In equivocal cases, the observation of total or near-total circumferential involvement is supportive, as is the presence of perineural tracking in tangential sections and intraneural involvement."

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Section: Reexcision Pnimentioning

confidence: 97%

Perineural Invasion

Dunn

Morgan

Beer

2009

Dermatologic Surgery

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“…Chronic pancreatitis sometimes displays perineural involvement 29,30 . The parotid nerve may display benign glandular inclusions 31 . In a report of intraneural benign glandular structures associated with a traumatic neuroma, Ide and Umemura 32 reminded us that certain normal structures of the head and neck could be confused with PNI.…”

mentioning

confidence: 99%

Histologic mimics of perineural invasion

et al. 2009

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“…In our review of the literature we only found one report describing intraneural benign salivary gland inclusions at the periphery of a mucoepidermoid carcinoma, which did not, itself, exhibit perineural invasion. 8 We inquired with Dr Gary Ellis, Director of Oral & Maxillofacial Pathology Department, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah, a man with great experience in the field. He told us that he had seen a similar case many years ago, in a benign mixed tumor located in the parotid gland.…”

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confidence: 99%