Benign Mesotheliomas of Testicular Appendages: A Morphologic and Histochemical Study of Seven Cases And Review of Theories of Histogenesis

Stavrides, Alexander; Hutcheson, James B.

doi:10.1016/s0022-5347(17)65736-7

Cited by 33 publications

(7 citation statements)

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“…The histological features are of a gland‐like structure with cuboidal cells; the stroma is fibrous and dense. Their mesothelial origin is controversial, but like normal mesothelial cells, the tumour may produce hyaluronic acid which, in association with cellular architecture, supports this embryological theory [3, 6–9]. Because reports about the presentation and management of these tumours are rare, and because early surgical treatment is important in testicular malignancies, the diagnosis of testicular adenomatoid tumour remains one of exclusion.…”

Section: Discussionmentioning

confidence: 99%

Testicular adenomatoid tumours: clinical and ultrasonographic characteristics

Kassis¹

2000

BJU International

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Objective To determine if benign testicular tumours can be identi®ed clinically and ultrasonographically before surgery. Patients and methods The clinical and ultrasonographic ®ndings of six patients with testicular adenomatoid tumours and 16 with testicular germ cell tumours were assessed retrospectively and compared. Results All adenomatoid tumours were characterized on physical examination by a well-de®ned, painful and un®xed nodule, contrasting with the painless and illde®ned malignant lesions. On ultrasonography, of the six adenomatoid tumours, two appeared hypoechoic, one hyperechoic, two isoechoic and one was normal, whereas none of the 16 tumours appeared normal or isoechoic. Conclusions While isoechogenicity was not apparent in the group of testicular malignancies, the two groups had hypo-and hyperechoic patterns. Small, super®cial, painful and un®xed testicular tumours that appear isoechoic on ultrasonography should be biopsied through an inguinal approach, with frozen sections assessed, instead of the patients undergoing immediate radical orchidectomy.

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Section: Discussionmentioning

confidence: 99%

Testicular adenomatoid tumours: clinical and ultrasonographic characteristics

Kassis¹

2000

BJU International

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“…Adenomatous tumors are the most common neoplasms of the paratesticular tissues", 46 but the majority are small and rarely measure more than 3 cm in diameter. Stavrides and Hutcheson46 found approximately 130 examples in the literature in their review in 1960.…”

Section: Discussionmentioning

confidence: 99%

Testicular and paratesticular neoplasms in patients 60 years of age and older

Abell

Holtz

1968

Cancer

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Testicular and paratesticular neoplasms from 50 patients 60 years of age or older were assessed with respect to histologic type, clinical findings and outcome. Neoplasms of germ cell origin comprised 24% of the series; there were ten seminomas and two teratocarcinomas. The seminomas were palpable many months before diagnosis and were larger than the other neoplasms. Only two deaths could be attributed to their dissemination. Both teratocarcinomas metastasized and caused death. There were five gonadal stromal neoplasms (10%), one Sertoli cell tumor, three interstitial cell tumors and one undifferentiated stromal tumor. None of the neoplasms recurred or metastasized. Eleven neoplasms (22%) were of supportive tissue or paratesticular origin and six of these arose from muscle—one leiomyoma, two leiomyosarcomas and three rhabdomyo‐sarcomas. The other tumors were two malignant mesotheliomas, one fibroma, one fibrosarcoma and one carcinoma of the epididymis. The lymphoreticular neoplasms were the most common lesion in this series and presented as primary testicular tumors in 22 patients (44%). In five patients asynchronous tumors appeared in the other testes. All but two neoplasms were reticulum cell sarcomas. All patients for whom survival information was available died with disseminated disease.

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“…Synonyms for adenomatoid tumors are adenomyoma, adenofibroma, angioma, angiosarcoma, lymphadenoma, leiomyoma, and low-grade adenocarcinoma [17], More than 355 cases have been described up to 1977 [19], The origin of adenomatoid tumors from either the endothe lium, the mesonephros, or Miiller's duct is a matter of discussion [18,[20][21][22][23], Several similar histochemical and ultrastructural features between adenomatoid tumors and epididymal duct cells were found. Based on these find ings, it is suggested that the adenomatoid tumor is de rived from the coelomic epithelium after it has begun to differentiate in the direction of genital epithelia [24].…”

Section: Adenomatoid Tumorsmentioning

confidence: 99%